Drosophila Melanogaster bsk Recombinant Protein – Cat# MBS1127548

Stress-Activated Protein Kinase JNK (bsk) Drosophila Melanogaster Recombinant Protein

Name: bsk Recombinant Protein; Drosophila Melanogaster; MyBioSource
Brand: MyBioSource
SKU: MBS1127548
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1127548

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Stress-activated protein kinase JNK (bsk), Recombinant Protein

Full Product Name

Recombinant Drosophila melanogaster Stress-activated protein kinase JNK (bsk)

Product Gene Name

bsk recombinant protein

Product Synonym Gene Name

bsk; JNK; CG5680

Product Synonym Names

Stress-activated protein kinase JNK; dJNK; EC=2.7.11.24; Protein basket

Sequence

MTTAQHQHYT VEVGDTNFTI HSRYINLRPI GSGAQGIVCA AYDTITQQNV AIKKLSRPFQ NVTHAKRAYR EFKLMKLVNH KNIIGLLNAF TPQRNLEEFQ DVYLVMELMD ANLCQVIQMD LDHDRMSYLL YQMLCGIKHL HSAGIIHRDL KPSNIVVKAD CTLKILDFGL ARTAGTTFMM TPYVVTRYYR APEVILGMGY TENVDIWSVG CIMGEMIRGG VLFPGTDHID QWNKIIEQLG TPSPSFMQRL QPTVRNYVEN RPRYTGYSFD RLFPDGLFPN DNNQNSRRKA SDARNLLSKM LVIDPEQRIS VDEALKHEYI NVWYDAEEVD APAPEPYDHS VDEREHTVEQ WKELIYEEVM DYEAHNTNNR TR

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

45 kDa

Sequence Positions

1-372. Full-length.

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P92208

Species

Drosophila melanogaster (Fruit fly)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of bsk recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for bsk purchase

MBS1127548 is a recombinant protein targeting bsk. Also known as Recombinant Drosophila melanogaster Stress-activated protein kinase JNK (bsk). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for bsk. It may not necessarily be applicable to this product.

NCBI GI #

281364754

NCBI GeneID

44801

NCBI Accession #

NP_001162930.1

UniProt Primary Accession #

P92208

UniProt Secondary Accession #

O01366; Q94542

UniProt Related Accession #

P92208

GenBank Nucleotide #

NM_001169459.1

NCBI Official Full Name

basket, isoform F

NCBI Official Synonym Full Names

basket

NCBI Official Symbol

bsk

NCBI Official Synonym Symbols

Bsk; BSK; CG5680; D-JNK; D-junk; DBSK/JNK; dJNK; DJNK; DJNK/bsk; DmelCG5680; jnk; Jnk; JNK; JNK/SAPK; Junk; pJNK; SAPKa

UniProt Protein Name

Stress-activated protein kinase JNK

UniProt Synonym Protein Names

Protein basket

UniProt Gene Name

bsk

UniProt Synonym Gene Names

JNK; dJNK

UniProt Entry Name

JNK_DROME

NCBI Protein Information

CG5680 gene product from transcript CG5680-RB; CG5680-PB; CG5680-PE; CG5680-PF; JNK; JUN kinase; Jun N-terminal kinase; Jun NH2-terminal kinase; Jun-N-terminal kinase; Jun-kinase; basket; bsk-PB; bsk-PE; bsk-PF; c-Jun N-terminal kinase; c-Jun aminoterminal kinase; c-Jun-N-terminal kinase; pJNK

UniProt Comments for bsk

Responds to activation by environmental stress by phosphorylating a number of transcription factors, primarily components of AP-1 such as Jra and also the transcriptional repressor aop, and thus regulates transcriptional activity (PubMed:9224720). Component of the immune response activated by bacterial infection, and is involved in wound healing and in dorsal closure, a morphogenetic movement during embryogenesis (PubMed:8946915, PubMed:9224720, PubMed:10433922, PubMed:11784101). Functions in the systematic response to wounding acting downstream of the Hayan-phenoloxidase PPO1 cascade (PubMed:22227521). Exhibits cytoprotective activity in neuronal cells in response to wounding to the integument (PubMed:22227521). Controls the expression of a phosphatase, puckered, at the edges of wounded epidermal tissue and in the dorsal epithelium during dorsal closure (PubMed:10433922, PubMed:11784101).

Research Articles on bsk

1. Data show that the actin-Capping Protein (CP) alphabeta heterodimer, which regulates actin filament (F-actin) polymerization, limits Src-induced apoptosis or tissue overgrowth by restricting JNK activation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with bsk recombinant protein

Products by Pathway	Pathway Diagram
Activated TLR4 Signalling Pathway antibodies	Activated TLR4 Signalling Pathway Diagram
Activation Of The AP-1 Family Of Transcription Factors Pathway antibodies	Activation Of The AP-1 Family Of Transcription Factors Pathway Diagram
Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies	Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Cellular Senescence Pathway antibodies	Cellular Senescence Pathway Diagram
Cellular Responses To Stress Pathway antibodies	Cellular Responses To Stress Pathway Diagram
DSCAM Interactions Pathway antibodies	DSCAM Interactions Pathway Diagram
FCERI Mediated MAPK Activation Pathway antibodies	FCERI Mediated MAPK Activation Pathway Diagram
Fc Epsilon Receptor (FCERI) Signaling Pathway antibodies	Fc Epsilon Receptor (FCERI) Signaling Pathway Diagram
FoxO Signaling Pathway antibodies	FoxO Signaling Pathway Diagram

Diseases associated with bsk recombinant protein

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>14 publications with bsk and Immune System Diseases
Death Antibodies	>7 publications with bsk and Death
Inflammation Antibodies	>7 publications with bsk and Inflammation
Brain Diseases Antibodies	>6 publications with bsk and Brain Diseases
Kidney Diseases Antibodies	>5 publications with bsk and Kidney Diseases
Heart Diseases Antibodies	>4 publications with bsk and Heart Diseases
Hyperplasia Antibodies	>3 publications with bsk and Hyperplasia
Necrosis Antibodies	>3 publications with bsk and Necrosis
Lung Diseases Antibodies	>2 publications with bsk and Lung Diseases
Memory Disorders Antibodies	>2 publications with bsk and Memory Disorders

Organs/Tissues associated with bsk recombinant protein

Organ/Tissue Name	Pubmed Publications
Head Antibodies	>10 publications with bsk and Head
Gonad Antibodies	>3 publications with bsk and Gonad
Fat Body Antibodies	>1 publications with bsk and Fat Body