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Modulator of Ftsh Protease Hflc (hflC) Escherichia Coli Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1128931

MBS1128931 is a recombinant protein targeting hflC. Also known as Recombinant Escherichia coli Modulator of FtsH protease HflC (hflC), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1500 / 0.5 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Modulator of FtsH protease HflC (hflC), Recombinant Protein
Full Product Name
Recombinant Escherichia coli Modulator of FtsH protease HflC (hflC), partial
Product Gene Name
Sequence
MRKSVIAIII IVLVVLYMSV FVVKEGERGI TLRFGKVLRD DDNKPLVYEP GLHFKIPFIE TVKMLDARIQ TMDNQADRFV TKEKKDLIVD SYIKWRISDF SRYYLATGGG DISQAEVLLK RKFSDRLRSE IGRLDVKDIV TDSRGRLTLE VRDALNSGSA GTEDEVTTPA ADNAIAEAAE RVTAETKGKV PVINPNSMAA LGIEVVDVRI KQINLPTEVS EAIYNRMRAE REAVARRHRS QGQEEAEKLR ATADYEVTRT LAEAERQGRI MRGEGDAEAA KLFADAFSKD PDFYAFIRSL RAYENSFSGN QDVMVMSPDS DFFRYMKTPT SATR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
37,650 Da
Sequence Positions
1-334
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P0ABC3
Species
Escherichia coli (strain K12)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of hflC recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for hflC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
GenBank Nucleotide #
NCBI Official Full Name
HflB protease modulator specific for phage lambda cII repressor
NCBI Official Symbol
hflC
NCBI Official Synonym Symbols
ECK4171; hflA; JW4133
UniProt Protein Name
Modulator of FtsH protease HflC
UniProt Gene Name
hflC
UniProt Synonym Gene Names
hflA
NCBI Protein Information
HflB protease modulator specific for phage lambda cII repressor

NCBI Summary for hflC

Gain-of-function alleles in hflC and hflK inhibit FtsH-mediated degradation of uncomplexed SecY protein and other membrane protein substrates. [More information is available at EcoGene: EG10435]. The HflK-HflC (HflKC) complex interacts with FtsH and regulates (inhibits) proteolysis by FtsH of SecY and lambda cII protein . [More information is available at EcoCyc: EG10435].
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UniProt Comments for hflC

HflC and HflK help govern the stability of phage lambda cII protein, and thereby control the lysogenization frequency of phage lambda. HflKC inhibits the SecY-degrading activity of FtsH, possibly helping quality control of integral membrane proteins.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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