Human Herpesvirus 2 UL27 Recombinant Protein – Cat# MBS1138391

Envelope Glycoprotein B (Gb) (UL27) Human Herpesvirus 2 Recombinant Protein

Name: UL27 Recombinant Protein; Human Herpesvirus 2; MyBioSource
Brand: MyBioSource
SKU: MBS1138391
Price: 385 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1138391

Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into… More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Envelope glycoprotein B (gB) (UL27), Recombinant Protein

Full Product Name

Recombinant Human herpesvirus 2 Envelope glycoprotein B (gB)

Product Gene Name

UL27 recombinant protein

Product Synonym Gene Name

gB; UL27

Product Synonym Names

Recombinant Envelope glycoprotein B (gB); Envelope glycoprotein B; gB; gB-2 gB2

Sequence

APAAPAAPRA SGGVAATVAA NGGPASRPPP VPSPATTKAR KRKTKKPPKR PEATPPPDAN ATVAAGHATL RAHLREIKVE NADAQFYVCP PPTGATVVQF EQPRRCPTRP EGQNYTEGIA VVFKENIAPY KFKATMYYKD VTVSQVWFGH RYSQFMGIFE DRAPVPFEEV IDKINTKGVC RSTAKYVRNN METTAFHRDD HETDMELKPA KVATRTSRGW HTTDLKYNPS RVEAFHRYGT TVNCIVEEVD ARSVYPY

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

44.4 kDa

Sequence Positions

23-279aa; Partial

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

NC_001798.1 (53367..56117, complement)

3D Structure

ModBase 3D Structure for P08666

Species

Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2)

Production Note

Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of UL27 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UL27 purchase

MBS1138391 is a recombinant protein targeting UL27. Also known as Recombinant Human herpesvirus 2 Envelope glycoprotein B (gB). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for UL27. It may not necessarily be applicable to this product.

NCBI GI #

9629297

NCBI GeneID

1487312

NCBI Accession #

NP_044497.1

UniProt Primary Accession #

P08666

UniProt Secondary Accession #

P89450

GenBank Nucleotide #

NC_001798.1

NCBI Official Full Name

envelope glycoprotein B

NCBI Official Symbol

UL27

UniProt Protein Name

Envelope glycoprotein B

UniProt Synonym Protein Names

gB-2; gB2

Protein Family

Protein

UniProt Gene Name

UniProt Synonym Gene Names

UniProt Entry Name

GB_HHV2H

NCBI Protein Information

type 1 membrane protein; contains a signal peptide; possible membrane fusogen; binds cell surface heparan sulphate; envelope glycoprotein B

UniProt Comments for UL27

Function: Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding of gD to one of its receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress. Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).

Subunit structure: Homotrimer; disulfide-linked. Binds to heparan sulfate proteoglycans. Interacts with gD. Interacts with gH/gL heterodimer. Associates with the gB-gH/gL-gD complex

By similarity.

Subcellular location: Virion membrane; Single-pass type I membrane protein

By similarity. Host cell membrane; Single-pass type I membrane protein

By similarity. Host endosome membrane; Single-pass type I membrane protein

By similarity. Host Golgi apparatus membrane; Single-pass type I membrane protein

By similarity. Note: During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN)

By similarity.

Sequence similarities: Belongs to the herpesviridae glycoprotein B family.

Research Articles on UL27

1. Glycoprotein B intracellular conformation is altered by low pH.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.