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CMT1A Duplicated Region Transcript 1 Protein (CDRT1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1144605

MBS1144605 is a recombinant protein targeting CDRT1. Also known as Recombinant Human CMT1A duplicated region transcript 1 protein (CDRT1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1615 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CMT1A duplicated region transcript 1 protein (CDRT1), Recombinant Protein
Full Product Name
Recombinant Human CMT1A duplicated region transcript 1 protein (CDRT1)
Product Gene Name
CDRT1 recombinant protein
Sequence
MENLESRLKN APYFRCEKGT DSIPLCRKCE TRVLAWKIFS TKEWFCRIND ISQRRFLVGI LKQLNSLYLL HYFQNILQTT QGKDFIYNRS RIDLSKKEGK VVKSSLNQML DKTVEQKMKE ILYWFANSTQ WTKANYTLLL LQMCNPKLLL TAANVIRVLF LREENNISGL NQDITDVCFS PEKDHSSKSA TSQVYWTAKT QHTSLPLSKA PENEHFLGAA SNPEEPWRNS LRCISEMNRL FSGKADITKP GYDPCNLLVD LDDIRDLSSG FSKYRDFIRY LPIHLSKYIL RMLDRHTLNK CASVSQHWAA MAQQVKMDLS AHGFIQNQIT FLQGSYTRGI DPNYANKVSI PVPKMVDDGK SMRVKHPKWK LRTKNEYNLW TAYQNEETQQ VLMEERNVFC GTYNVRILSD TWDQNRVIHY SGGDLIAVSS NRKIHLLDII QVKAIPVEFR GHAGSVRALF LCEEENFLLS GSYDLSIRYW DLKSGVCTRI FGGHQGTITC MDLCKNRLVS GGRDCQVKVW DVDTGKCLKT FRHKDPILAT RINDTYIVSS CERGLVKVWH IAMAQLVKTL SGHEGAVKCL FFDQWHLLSG STDGLVMAWS MVGKYERCLM AFKHPKEVLD VSLLFLRVIS ACADGKIRIY NFFNGNCMKV IKANGRGDPV LSFFIQGNRI SVCHISTFAK RINVGWNGIE PSATAQGGNA SLTECAHVRL HIAGHLPASR LPVAAVQPMT GGMAPTTAPT HVLAMLILFS GV
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
27,567 Da
Sequence Positions
1-752, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
604596
3D Structure
ModBase 3D Structure for O95170
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CDRT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CDRT1. It may not necessarily be applicable to this product.

NCBI GI #
157694487
NCBI GeneID
374286
NCBI Accession #
NP_006373.2
UniProt Primary Accession #
O95170
UniProt Secondary Accession #
O43848; O95611
UniProt Related Accession #
O95170
GenBank Nucleotide #
NM_006382.3
NCBI Official Full Name
CMT1A duplicated region transcript 1 protein isoform a
NCBI Official Synonym Full Names
CMT1A duplicated region transcript 1
NCBI Official Symbol
CDRT1
NCBI Official Synonym Symbols
HREP; SM25H2; C170RF1; C17ORF1; FBXW10B; C17ORF1A; FBXW10P1
UniProt Protein Name
CMT1A duplicated region transcript 1 protein
Protein Family
CMT1A duplicated region transcript 1 protein
UniProt Gene Name
CDRT1
UniProt Synonym Gene Names
C17orf1; C17orf1A; HREP
NCBI Protein Information
CMT1A duplicated region transcript 1 protein

NCBI Summary for CDRT1

Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
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UniProt Comments for CDRT1

MiscellaneousCDRT1 gene is located centromeric to and partially within proximal CMT1A-REP element. CMT1A-REP is a complex binary repeat element flanking a 1.5-Mb DNA region duplicated in Charcot-Marie-Tooth disease type I (CMT1A) or deleted in Hereditary neuropathy (HNPP).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CDRT1 recombinant protein

 Reference Product  PubMed Publications
 PMP22 recombinant protein  >10 publications with CDRT1 and PMP22
 COX10 recombinant protein  >2 publications with CDRT1 and COX10
 CDRT15 recombinant protein  >1 publications with CDRT1 and CDRT15

Diseases associated with CDRT1 recombinant protein

 Disease Name  Pubmed Publications
 Peripheral Nervous System Diseases Antibodies  >15 publications with CDRT1 and Peripheral Nervous System Diseases
 Nervous System Diseases Antibodies  >15 publications with CDRT1 and Nervous System Diseases

Organs/Tissues associated with CDRT1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with CDRT1 and Brain
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