Human Herpesvirus 1 UL40 Recombinant Protein – Cat# MBS1145207

Ribonucleoside-Diphosphate Reductase Small Chain (UL40) Human Herpesvirus 1 Recombinant Protein

Name: UL40 Recombinant Protein; Human Herpesvirus 1; MyBioSource
Brand: MyBioSource
SKU: MBS1145207
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1145207

MBS1145207 is a recombinant protein targeting UL40. Also known as Recombinant Human herpesvirus 1 Ribonucleoside-diphosphate reductase small chain (UL40). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ribonucleoside-diphosphate reductase small chain (UL40), Recombinant Protein

Full Product Name

Recombinant Human herpesvirus 1 Ribonucleoside-diphosphate reductase small chain (UL40)

Product Gene Name

UL40 recombinant protein

Product Synonym Gene Name

Recombinant Ribonucleoside-diphosphate reductase small chain (UL40); Ribonucleoside-diphosphate reductase small chain; R2 EC= 1.17.4.1; Ribonucleotide reductase 38 kDa subunit Ribonucleotide reductase small subunit

Sequence

DLAIQIPKCP DPERYFYTSQ CPDINHLRSL SILNRWLETE LVFVGDEEDV SKLSEGELSF YRFLFAFLSA ADDLVTENLG GLSGLFEQKD ILHYYVEQEC IEVVHSRVYN IIQLVLFHNN DQARREYVAG TINHPAIRAK VDWLEARVRE CASVPEKFIL MILIEGIFFA ASFAAIAYLR TNNLLRVTCQ SNDLISRDEA VHTTASCYIY NNYLGGHAKP PPDRVYGLFR QAVEIEIGFI RSQAPTDSHI LSPAALAAIE NYVRFSADRL LGLIHMKPLF SAPPPDASFP LSLMSTDKHT NFFECRSTSY AGAVVNDL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

38,019 Da

Sequence Positions

23-340

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

NC_001806.1 (89773..90988)

3D Structure

ModBase 3D Structure for P10224

Species

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of UL40 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UL40. It may not necessarily be applicable to this product.

NCBI GI #

9629421

NCBI GeneID

2703364

NCBI Accession #

NP_044642.1

UniProt Primary Accession #

P10224

UniProt Secondary Accession #

Q09I93; B9VQG8

UniProt Related Accession #

BAA01686

GenBank Nucleotide #

NC_001806.1

NCBI Official Full Name

ribonucleotide reductase subunit 2

NCBI Official Symbol

UL40

UniProt Protein Name

Ribonucleoside-diphosphate reductase small chain

UniProt Synonym Protein Names

Ribonucleotide reductase 38 kDa subunit; Ribonucleotide reductase small subunit

Protein Family

Protein

UniProt Gene Name

UniProt Synonym Gene Names

UniProt Entry Name

RIR2_HHV11

NCBI Protein Information

ribonucleotide reductase subunit 2

UniProt Comments for UL40

Function: Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis. Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. The N-terminal region confers antiapoptotic activity in differentiated cells such as neurons and is important for viral reactivation to increase neural survivability

By similarity.

Catalytic activity: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.

Cofactor: Binds 2 iron ions per subunit

By similarity.

Pathway: Genetic information processing; DNA replication.

Subunit structure: Heterotetramer composed of a homodimer of the large subunit UL39 (R1) and a homodimer of the small subunit UL40 (R2). Larger multisubunit protein complex are also active, composed of (R1)n(R2)n

By similarity.

Subcellular location: Host membrane; Single-pass membrane protein

Potential.

Sequence similarities: Belongs to the ribonucleoside diphosphate reductase small chain family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.