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Leukotoxin Translocation ATP-Binding Protein Lktb (lktB) Pasteurella Haemolytica Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1151611

MBS1151611 is a recombinant protein targeting lktB. Also known as Recombinant Pasteurella haemolytica Leukotoxin translocation ATP-binding protein LktB (lktB). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Leukotoxin translocation ATP-binding protein LktB (lktB), Recombinant Protein
Full Product Name
Recombinant Pasteurella haemolytica Leukotoxin translocation ATP-binding protein LktB (lktB)
Product Gene Name
Product Synonym Gene Name
lktB
Product Synonym Names
Recombinant Leukotoxin translocation ATP-binding protein LktB (lktB); Leukotoxin translocation ATP-binding protein LktB EC= 3.6.3.43
Sequence
MEANHQRNDL GLVALTMLAQ YHNISLNPEE IKHKFDLDGK GLSLTAWLLA AKSLALKAKH IKKEISRLHL VNLPALVWQD NGKHFLLVKV DTDNNRYLTY NLEQDAPQIL SQDEFEACYQ GQLILVTSRA SVVGQLAKFD FTWFIPAVIK YRKIFLETLI VSIFLQIFAL ITPLFFQVVM DKVLVHRGFS TLNIITVALA IVIIFEIVLS GLRTYVFSHS TSRIDVELGA KLFRHLLSLP ISYFENRRVG DTVARVRELD QIRNFLTGQA LTSVLDLLFS FIFFAVMWYY SPKLTLVILG SLPCYILWSI FISPILRRRL DEKFARSADN QAFLVESVTS INMIKAMAVA PQMTDTWDKQ LASYVSSSFR VTVLATIGQQ GVQLIQKTVM VINLWLGAHL VISGDLSIGQ LIAFNMLSGQ VIAPVIRLAQ LWQDFQQVGI SVTRLGDVLN SPTEQYQGKL SLPEIKGDIS FKNIRFRYKP DAPTILNNVN LEIRQGEVIG IVGRSGSGKS TLTKLLQRFY IPENGQVLID GHDLALADPN WLRRQIGVVL QDNVLLNRSI RENIALSDPG MPMERVIYAA KLAGAHDFIS ELREGYNTIV GEQGAGLSGG QRQRIAIARA LVNNPKILIF DEATSALDYE SEHIIMQNMQ KICQGRTVIL IAHRLSTVKN ADRIIVMEKG EIVEQGKHHE LLQNSNGLYS YLHQLQLN
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
79,713 Da
Sequence Positions
1-708
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P16532
Species
Pasteurella haemolytica (Mannheimia haemolytica)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of lktB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for lktB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
Leukotoxin translocation ATP-binding protein LktB
UniProt Protein Name
Leukotoxin translocation ATP-binding protein LktB
UniProt Gene Name
lktB
UniProt Entry Name
LKB1A_PASHA

UniProt Comments for lktB

Function: Part of the ABC transporter complex LktBD involved in leukotoxin export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation

Probable.

Catalytic activity: ATP + H2O + peptide(In) = ADP + phosphate + peptide(Out).

Subunit structure: Homodimer

By similarity.

Subcellular location: Cell inner membrane; Multi-pass membrane protein

Probable.

Domain: In LktB the peptidase C39 domain, the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.

Sequence similarities: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family. [View classification]Contains 1 ABC transmembrane type-1 domain.Contains 1 ABC transporter domain.Contains 1 peptidase C39 domain.

Caution: Leu-10 is present instead of the conserved Cys which is expected to be the active site residue of peptidase C39. Thus this protein is presumed to be without peptidase activity.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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