Rat PCDH8 Recombinant Protein – Cat# MBS1152849

Protocadherin-8 (PCDH8) Rat Recombinant Protein

Name: PCDH8 Recombinant Protein; Protocadherin-8; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS1152849
Price: 2080 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1152849

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally… More details

$2080 / 0.5 mg (E-Coli) +2 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Protocadherin-8 (Pcdh8), Recombinant Protein

Full Product Name

Recombinant Rat Protocadherin-8 (Pcdh8), partial

Product Gene Name

Pcdh8 recombinant protein

Sequence

K TVRYSTFEED APGTVIGTLA EDLHMKVSGD TSFRLMKQFN SSLLRVREGD GQLTVGDAGL DRERLCGQSP QCVLAFDVVS FSQEQFRLVH VEVEVRDVND HAPRFPRAQI PVEVSESAPV GTRIPLEVPV DEDVGANGLQ SVRLAEPHSP FRVELQTRAD GAQCADLVLL QELDRESQAS YSLELVAQDG GRPPRSATAA LSVRVLDAND HSPAFPQGAV AEVELAEDAP VGSLLLDLDA ADPDEGPNGD VVFTFGARTP PEARHLFRLD PRSGRLTLAG QVDYERQDTY ELDVRAQDRG PGPRTATCKV IVRIRDVNDN APDISITPLA APGAPATSPF AAAAAAAALG GADAASSAGS GTQETGVTSL VPEGAARESL VALVSTSDRD SGANGQVRCA LYGHEHFRLQ PAYAGSYLVV TAASLDRERI AEYNLTLVAE DRGAPPLRTV RPYTVRVGDE NDNAPLFTKP VYEVSVRENN PPGAYLATVA ARDPDLGRNG QVTYRLVEAE VGRSGEAVST YVSVDPATGA IYALRSFDYE TLRQLDVRVQ ASDGGSPQLS SNALVQVRVL DQNDHSPVLV HPAPANGSLE VAVPGRSTKD TAVARIQARD ADEGANGELA FDLLQQEPRE AFSIGRHTGE IVLTGDLSQE PPGRVFKALL VISDGGRPPL TTTATVSFVV TAGGGSAVPA SAGSPEHFRP PGSRLAPSGP SLQWDTP

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

103,774 Da

Sequence Positions

30-747

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for D3ZE55

Species

Rat

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Pcdh8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pcdh8 purchase

MBS1152849 is a recombinant protein targeting Pcdh8. Also known as Recombinant Rat Protocadherin-8 (Pcdh8), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Pcdh8. It may not necessarily be applicable to this product.

NCBI GI #

12408332

NCBI GeneID

64865

NCBI Accession #

NP_074059.1

UniProt Primary Accession #

D3ZE55

UniProt Secondary Accession #

Q9WVR2; A1A5N4

UniProt Related Accession #

D3ZE55

GenBank Nucleotide #

NM_022868.1

NCBI Official Full Name

protocadherin-8

NCBI Official Synonym Full Names

protocadherin 8

NCBI Official Symbol

Pcdh8

NCBI Official Synonym Symbols

Arcadlin

UniProt Protein Name

Protocadherin-8

UniProt Synonym Protein Names

Activity-regulated cadherin-like protein; Arcadlin

Protein Family

Protocadherin

UniProt Gene Name

Pcdh8

UniProt Synonym Gene Names

Arcadlin

NCBI Protein Information

protocadherin-8

NCBI Summary for Pcdh8

may mediate activity-induced synaptic reorganization underlying long term memory [RGD, Feb 2006]

UniProt Comments for Pcdh8

Calcium-dependent cell-adhesion protein. May play a role in activity-induced synaptic reorganization underlying long term memory. Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis.

Research Articles on Pcdh8

1. Arcadlin knockout increases the number of dendritic spines, and the phenotype is rescued by siRNA knockdown of N-cadherin. T

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Pcdh8 recombinant protein

Reference Product	PubMed Publications
Mesp2 recombinant protein	>1 publications with Pcdh8 and Mesp2

Diseases associated with Pcdh8 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>5 publications with Pcdh8 and Nervous System Diseases
Chromosome Aberrations Antibodies	>3 publications with Pcdh8 and Chromosome Aberrations
Seizures Antibodies	>3 publications with Pcdh8 and Seizures
Nervous System Malformations Antibodies	>3 publications with Pcdh8 and Nervous System Malformations
Eye Diseases Antibodies	>2 publications with Pcdh8 and Eye Diseases
Abnormalities, Multiple Antibodies	>2 publications with Pcdh8 and Abnormalities, Multiple
Microcephaly Antibodies	>2 publications with Pcdh8 and Microcephaly
Disease Models, Animal Antibodies	>2 publications with Pcdh8 and Disease Models, Animal
Brain Diseases Antibodies	>2 publications with Pcdh8 and Brain Diseases
Cognition Disorders Antibodies	>1 publications with Pcdh8 and Cognition Disorders

Organs/Tissues associated with Pcdh8 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>11 publications with Pcdh8 and Brain