Lymphocytic Choriomeningitis Virus LCMVsSgp2 Recombinant Protein – Cat# MBS1157807

Nucleoprotein (N) (LCMVsSgp2) Lymphocytic Choriomeningitis Virus Recombinant Protein

Name: LCMVsSgp2 Recombinant Protein; Lymphocytic Choriomeningitis Virus; MyBioSource
Brand: MyBioSource
SKU: MBS1157807
Price: 1285 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1157807

MBS1157807 is a recombinant protein targeting LCMVsSgp2. Also known as Recombinant Lymphocytic choriomeningitis virus Nucleoprotein (N), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1285 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nucleoprotein (N) (LCMVsSgp2), Recombinant Protein

Full Product Name

Recombinant Lymphocytic choriomeningitis virus Nucleoprotein (N), partial

Product Gene Name

LCMVsSgp2 recombinant protein

Sequence

FALLGDFFRK SKEKIGKEFK RIVQRIKDFL RNLVPRTES

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

62,177 Da

Sequence Positions

132-170aa; Full Length of Mature Protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P09992

Species

Lymphocytic choriomeningitis virus (strain Armstrong) (LCMV)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LCMVsSgp2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LCMVsSgp2. It may not necessarily be applicable to this product.

NCBI GI #

23334590

NCBI GeneID

956592

NCBI Accession #

NP_694852.1

UniProt Primary Accession #

P09992

UniProt Secondary Accession #

Q49K86

GenBank Nucleotide #

NC_004294.1

NCBI Official Full Name

nucleoprotein

NCBI Official Symbol

LCMVsSgp2

UniProt Protein Name

Nucleoprotein

UniProt Synonym Protein Names

Nucleocapsid protein

UniProt Gene Name

NCBI Protein Information

nucleoprotein

UniProt Comments for LCMVsSgp2

Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation.

Research Articles on LCMVsSgp2

1. The viral nucleoprotein associates with double-stranded RNA (dsRNA)-activated protein kinase (PKR), a well-characterized antiviral protein that inhibits cap-dependent protein translation initiation via phosphorylation of eIF2alpha.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.