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Epithelial Cell Adhesion Molecule (EPCAM) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1160032

MBS1160032 is a recombinant protein targeting Epcam. Also known as Recombinant Rat Epithelial cell adhesion molecule (Epcam). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Epithelial cell adhesion molecule (Epcam), Recombinant Protein
Full Product Name
Recombinant Rat Epithelial cell adhesion molecule (Epcam)
Product Gene Name
Epcam recombinant protein
Product Synonym Gene Name
Epcam; Tacstd1
Product Synonym Names
Epithelial cell adhesion molecule; Ep-CAM; Epithelial glycoprotein 314; EGP314; Protein D5.7A; Tumor-associated calcium signal transducer 1; CD_antigen=; CD326
Sequence
QKDCVCN NYKLTSRCYE NENGECQCTS YGTQNTVICS KLASKCLVMK AEMTHSKSGR RMKPEGAIQN NDGLYDPECD EQGLFKAKQC NGTATCWCVN TAGVRRTDKD TEITCSERVR TYWIIIELKH KERAQPYNFE SLHTALQDTF ASRYMLNPKF IKSIMYENNV ITIDLMQNSS QKTQDDVDIA DVAYYFEKDV KGESLFHSSK SMDLRVNGEL LDLDPGQTLI YYVDEKAPEF SMQGLT
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
35,207 Da
Sequence Positions
24-266
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for O55159
Species
Rattus norvegicus (Rat)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Epcam recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Epcam. It may not necessarily be applicable to this product.

NCBI GI #
25742698
NCBI GeneID
171577
NCBI Accession #
NP_612550.1
UniProt Primary Accession #
O55159
UniProt Related Accession #
O55159
GenBank Nucleotide #
NM_138541.1
NCBI Official Full Name
epithelial cell adhesion molecule
NCBI Official Synonym Full Names
epithelial cell adhesion molecule
NCBI Official Symbol
Epcam
NCBI Official Synonym Symbols
Egp314; Tacstd1
UniProt Protein Name
Epithelial cell adhesion molecule
UniProt Synonym Protein Names
Epithelial glycoprotein 314; EGP314; Protein D5.7A; Tumor-associated calcium signal transducer 1; CD_antigen: CD326
Protein Family
Epithelial cell adhesion molecule
UniProt Gene Name
Epcam
UniProt Synonym Gene Names
Tacstd1; Ep-CAM; EGP314
UniProt Entry Name
EPCAM_RAT
NCBI Protein Information
epithelial cell adhesion molecule; ep-CAM; epithelial glycoprotein 314; tumor-associated calcium signal transducer 1

NCBI Summary for Epcam

involved in metastasis formation and tumor progression [RGD, Feb 2006]

UniProt Comments for Epcam

EPCAM: a single-pass type I membrane protein of the EPCAM family. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas including pancreatic carcinoma. May be a marker of cancer stem cells.

Protein type: Cell adhesion; Cell surface; Membrane protein, integral; Cell cycle regulation; Motility/polarity/chemotaxis

Cellular Component: tight junction; cell surface; basolateral plasma membrane; apical plasma membrane; plasma membrane; integral to membrane; lateral plasma membrane

Molecular Function: protein complex binding

Biological Process: ureteric bud development; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; stem cell differentiation; negative regulation of apoptosis
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Research Articles on Epcam

1. cld7 supports tumorigenic features of EpC by provoking EpC cleavage and thereby its cotranscription factor activity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Epcam recombinant protein

 Reference Product  PubMed Publications
 Cd44 recombinant protein  >142 publications with Epcam and Cd44
 Cdh1 recombinant protein  >13 publications with Epcam and Cdh1
 Cldn7 recombinant protein  >13 publications with Epcam and Cldn7
 Tspan8 recombinant protein  >5 publications with Epcam and Tspan8
 St14 recombinant protein  >3 publications with Epcam and St14
 Spint2 recombinant protein  >2 publications with Epcam and Spint2
 Bspry recombinant protein  >1 publications with Epcam and Bspry
 Ceacam1 recombinant protein  >1 publications with Epcam and Ceacam1

Diseases associated with Epcam recombinant protein

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >565 publications with Epcam and Carcinoma
 Neoplasm Metastasis Antibodies  >313 publications with Epcam and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >245 publications with Epcam and Adenocarcinoma
 Breast Neoplasms Antibodies  >198 publications with Epcam and Breast Neoplasms
 Liver Diseases Antibodies  >149 publications with Epcam and Liver Diseases
 Liver Neoplasms Antibodies  >148 publications with Epcam and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >124 publications with Epcam and Carcinoma, Hepatocellular
 Neoplasms, Experimental Antibodies  >99 publications with Epcam and Neoplasms, Experimental
 Carcinoma, Squamous Cell Antibodies  >83 publications with Epcam and Carcinoma, Squamous Cell
 Ovarian Neoplasms Antibodies  >83 publications with Epcam and Ovarian Neoplasms

Organs/Tissues associated with Epcam recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >166 publications with Epcam and Lung
 Colon Antibodies  >145 publications with Epcam and Colon
 Prostate Antibodies  >94 publications with Epcam and Prostate
 Kidney Antibodies  >43 publications with Epcam and Kidney
 Pancreas Antibodies  >39 publications with Epcam and Pancreas
 Thymus Antibodies  >19 publications with Epcam and Thymus
 Spleen Antibodies  >14 publications with Epcam and Spleen
 Testis Antibodies  >14 publications with Epcam and Testis
 Mammary Gland Antibodies  >13 publications with Epcam and Mammary Gland
 Placenta Antibodies  >4 publications with Epcam and Placenta
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