Rat KCNQ3 Recombinant Protein – Cat# MBS1167949

Potassium Voltage-Gated Channel Subfamily KQT Member 3 (KCNQ3) Rat Recombinant Protein

Name: KCNQ3 Recombinant Protein; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS1167949
Price: 3840 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1167949

MBS1167949 is a recombinant protein targeting Kcnq3. Also known as Recombinant Rat Potassium voltage-gated channel subfamily KQT member 3 (Kcnq3) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$3840 / 1 mg (E-Coli) +4 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Potassium voltage-gated channel subfamily KQT member 3 (Kcnq3), Recombinant Protein

Full Product Name

Recombinant Rat Potassium voltage-gated channel subfamily KQT member 3 (Kcnq3) , partial

Product Gene Name

Kcnq3 recombinant protein

Sequence

MGLKARRAAG AAGGGGGEGG GGGGGAANPA GGDSAVAGDE ERKVGLAPGD VEQVTLALGT GADKDGTLLL EGGGREEGQR RTPQGIGLLA KTPLSRPVKR NNAKYRRIQT LIYDALERPR GWALLYHALV FLIVLGCLIL AVLTTFKEYE TVSGDWLLLL ETFAIFIFGA EFALRIWAAG CCCRYKGWRG RLKFARKPLC MLDIFVLIAS VPVVAVGNQG NVLATSLRSL RFLQILRMLR MDRRGGTWKL LGSAICAHSK ELITAWYIGF LTLILSSFLV YLVEKDVPEM DAQGEEMKEE FETYADALWW GLITLATIGY GDKTPKTWEG RLIAATFSLI GVSFFALPAG ILGSGLALKV QEQHRQKHFE KRRKPAAELI QAAWRYYATN PNRLDLVATW RFYESVVSFP FFRKEQLEAA ASQKLGLLDR VRLSNPRGSN TKGKLFTPLN VDAIEESPSK EPKPVGLNNK ERFRTAFRMK AYAFWQSSED AGTGDPMTED RGYGNDFLIE DMIPTLKAAI RAVRILQFRL YKKKFKETLR PYDVKDVIEQ YSAGHLDMLS RIKYLQTRID MIFTPGPPST PKHKKSQKGS AFTYPSQQSP RNEPYVARAA TSETEDQSMM GKFVKVERQV HDMGKKLDFL VDMHMQHMER LQVHVTEYYP TKGASSPAEG EKKEDNRYSD LKTIICNYSE SGPPDPPYSF HQVPIDRVGP YGFFAHDPVK LTRGGPSSTK AQANLPSSGS TYAERPTVLP ILTLLDSCVS YHSQTELQGP YSDHISPRQR RSITRDSDTP LSLMSVNHEE LERSPSGFSI SQDRDDYVFG PSGGSSWMRE KRYLAEGETD TDTDPFTPSG SMPMSSTGDG ISDSIWTPSN KPT

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

93,601 Da

Sequence Positions

1-873

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O88944

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Kcnq3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Kcnq3. It may not necessarily be applicable to this product.

NCBI GI #

20141167

NCBI GeneID

29682

NCBI Accession #

O88944.2

UniProt Primary Accession #

O88944

UniProt Secondary Accession #

Q9Z240

UniProt Related Accession #

O88944

NCBI Official Full Name

Potassium voltage-gated channel subfamily KQT member 3

NCBI Official Synonym Full Names

potassium voltage-gated channel subfamily Q member 3

NCBI Official Symbol

Kcnq3

UniProt Protein Name

Potassium voltage-gated channel subfamily KQT member 3

UniProt Synonym Protein Names

KQT-like 3; Potassium channel subunit alpha KvLQT3; Voltage-gated potassium channel subunit Kv7.3

Protein Family

Potassium voltage-gated channel subfamily

UniProt Gene Name

Kcnq3

NCBI Protein Information

potassium voltage-gated channel subfamily KQT member 3

NCBI Summary for Kcnq3

potassium channel involved in regulating neuronal excitability [RGD, Feb 2006]

UniProt Comments for Kcnq3

Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability.

Research Articles on Kcnq3

1. KCNQ2 and KCNQ3 play an important role in neuronal differentiation of PC12 cells as measured by neurite growth. Depression of these KCNQs can promote neuronal differentiation, which is related to membrane depolarization and subsequent activation of Ca2+ influx through T type Ca2+ channels.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Kcnq3 recombinant protein

Reference Product	PubMed Publications
Kcnq2 recombinant protein	>279 publications with Kcnq3 and Kcnq2
Kcnq1 recombinant protein	>54 publications with Kcnq3 and Kcnq1
Kcnq4 recombinant protein	>42 publications with Kcnq3 and Kcnq4
Kcnh6 recombinant protein	>3 publications with Kcnq3 and Kcnh6
Kcnh5 recombinant protein	>1 publications with Kcnq3 and Kcnh5

Pathways associated with Kcnq3 recombinant protein

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Cholinergic Synapse Pathway antibodies	Cholinergic Synapse Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Interaction Between L1 And Ankyrins Pathway antibodies	Interaction Between L1 And Ankyrins Pathway Diagram
L1CAM Interactions Pathway antibodies	L1CAM Interactions Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram
Potassium Channels Pathway antibodies	Potassium Channels Pathway Diagram
Voltage Gated Potassium Channels Pathway antibodies	Voltage Gated Potassium Channels Pathway Diagram

Diseases associated with Kcnq3 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>113 publications with Kcnq3 and Nervous System Diseases
Epilepsy, Benign Neonatal Antibodies	>84 publications with Kcnq3 and Epilepsy, Benign Neonatal
Seizures Antibodies	>70 publications with Kcnq3 and Seizures
Pain Antibodies	>19 publications with Kcnq3 and Pain
Long QT Syndrome Antibodies	>9 publications with Kcnq3 and Long QT Syndrome
Arrhythmias, Cardiac Antibodies	>5 publications with Kcnq3 and Arrhythmias, Cardiac
Migraine Disorders Antibodies	>5 publications with Kcnq3 and Migraine Disorders
Chromosome Aberrations Antibodies	>3 publications with Kcnq3 and Chromosome Aberrations
Dizziness Antibodies	>1 publications with Kcnq3 and Dizziness
Fibrosis Antibodies	>1 publications with Kcnq3 and Fibrosis

Organs/Tissues associated with Kcnq3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>76 publications with Kcnq3 and Brain
Mixed Antibodies	>1 publications with Kcnq3 and Mixed