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Potassium Voltage-Gated Channel Subfamily KQT Member 1 (kcnq1) Xenopus Laevis Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1177637

MBS1177637 is a recombinant protein targeting kcnq1. Also known as Recombinant Xenopus laevis Potassium voltage-gated channel subfamily KQT member 1 (kcnq1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. kcnq1; kvlqt1 More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Potassium voltage-gated channel subfamily KQT member 1 (kcnq1), Recombinant Protein
Full Product Name
Recombinant Xenopus laevis Potassium voltage-gated channel subfamily KQT member 1 (kcnq1)
Product Gene Name
Product Synonym Gene Name
Recombinant Potassium voltage-gated channel subfamily KQT member 1 (kcnq1); Potassium voltage-gated channel subfamily KQT member 1; IKs producing slow voltage-gated potassium channel subunit alpha xKvLQT1 KQT-like 1 Voltage-gated potassium channel subunit Kv7.1
Sequence
MNENAINSLY EAIPLPQDGS SNGQRQEDRQ ANSFELKRET LVATDPPRPT INLDPRVSIY SGRRPLLSRT NIQGRVYNFL ERPTGWKCFV YHFTVFLIVL ICLIFSVLST IQQYNNLATE TLFWMEIVLV VFFGAEYVVR LWSAGCRSKY VGVWGRLRFA RKPISVIDLI VVVASVIVLC VGSNGQVFAT SAIRGIRFLQ ILRMLHVDRQ GGTWRLLGSV VFIHRQELIT TLYIGFLGLI FSSYFVYLAE KDAIDSSGEY QFGSYADALW WGVVTVTTIG YGDKVPQTWI GKTIASCFSV FAISFFALPA GILGSGFALK VQQKQRQKHF NRQIPAAASL IQTAWRCYAA ENPDSATWKI YIRKQSRNHH IMSPSPK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
42,645 Da
Sequence Positions
1-377
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P70057
Species
Xenopus laevis (African clawed frog)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of kcnq1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for kcnq1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Potassium voltage-gated channel subfamily KQT member 1
UniProt Protein Name
Potassium voltage-gated channel subfamily KQT member 1
UniProt Synonym Protein Names
IKs producing slow voltage-gated potassium channel subunit alpha xKvLQT1; KQT-like 1; Voltage-gated potassium channel subunit Kv7.1
UniProt Gene Name
kcnq1
UniProt Synonym Gene Names
kvlqt1
UniProt Entry Name
KCNQ1_XENLA

UniProt Comments for kcnq1

Function: Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current.

Subunit structure: Heterotetramer with KCNE1 (MinK) or KCNE3 (MiRP2). Interacts with CALM

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein

By similarity.

Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position

By similarity.

Sequence similarities: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily. [View classification]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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