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E3 Ubiquitin-Protein Ligase RMA1 (RMA1) Arabidopsis Thaliana Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1179787

MBS1179787 is a recombinant protein targeting RMA1. Also known as Recombinant Arabidopsis thaliana E3 ubiquitin-protein ligase RMA1 (RMA1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. RMA1 More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
E3 ubiquitin-protein ligase RMA1 (RMA1), Recombinant Protein
Full Product Name
Recombinant Arabidopsis thaliana E3 ubiquitin-protein ligase RMA1 (RMA1)
Product Gene Name
RMA1 recombinant protein
Product Synonym Gene Name
Recombinant E3 ubiquitin-protein ligase RMA1 (RMA1); E3 ubiquitin-protein ligase RMA1 EC= 6.3.2.-; Protein RING membrane-anchor 1
Sequence
MALDQSFEDA ALLGELYGEG AFCFKSKKPE PITVSVPSDD TDDSNFDCNI CLDSVQEPVV TLCGHLFCWP CIHKWLDVQS FSTSDEYQRH RQCPVCKSKV SHSTLVPLYG RGRCTTQEEG KNSVPKRPVG PVYRLEMPNS PYASTDLRLS QRVHFNSPQE GYYPVSGVMS SNSLSYSAVL DPVMVMVGEM VATRLFGTRV MDRFAYPDTY NLAGTSGPRM RRRIMQADKS LGRIFFFFMC CVVLCLLLF
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
28,012 Da
Sequence Positions
1-249
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 4; NC_003075.7 (1557120..1559428, complement). Location: chromosome: 4
3D Structure
ModBase 3D Structure for O64425
Species
Arabidopsis thaliana (Mouse-ear cress)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RMA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RMA1. It may not necessarily be applicable to this product.

NCBI GI #
15236326
NCBI GeneID
825654
NCBI Accession #
NP_192260.1
UniProt Primary Accession #
O64425
UniProt Related Accession #
O64425
GenBank Nucleotide #
NM_116589.3
NCBI Official Full Name
E3 ubiquitin-protein ligase RMA1
NCBI Official Symbol
RMA1
NCBI Official Synonym Symbols
ATRMA1; F9H3.14; F9H3_14; RING membrane-anchor 1; RMA1
UniProt Protein Name
E3 ubiquitin-protein ligase RMA1
UniProt Synonym Protein Names
Protein RING membrane-anchor 1
Protein Family
E3 ubiquitin-protein ligase
UniProt Gene Name
RMA1
UniProt Entry Name
RMA1_ARATH
NCBI Protein Information
E3 ubiquitin-protein ligase RMA1

NCBI Summary for RMA1

RMA1 encodes a novel 28 kDa protein with a RING finger motif and a C-terminal membrane-anchoring domain that is involved in the secretory pathway. Has E3 ubiquitin ligase activity.

UniProt Comments for RMA1

Function: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of aquaporin PIP2-1. Forms a ubiquitin ligase complex in cooperation with the E2 enzymes UCB8/UCB10. Ref.5 Ref.6 Ref.7

Pathway: Protein modification; protein ubiquitination.

Subcellular location: Endoplasmic reticulum membrane; Single-pass type IV membrane protein Ref.5 Ref.6 Ref.7.

Tissue specificity: Ubiquitous. Highly expressed in roots. Ref.1 Ref.6

Domain: The RING-type zinc finger domain is required for E3 ligase activity.The C-terminal transmembrane is dispensable for the ubiquitin ligase activity in vitro, but is critical for correct subcellular localization and substrate recognition in vivo.

Disruption phenotype: No visible phenotype and no effect on drought stress response, probably due to the redundancy with RMA2 and RMA3. Ref.7

Sequence similarities: Contains 1 RING-type zinc finger.
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Research Articles on RMA1

1. RMA1, RMA2 and RMA3 all have E3 ubiquitin ligase activity and are localized to the endoplasmic reticulum.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with RMA1 recombinant protein

 Products by Pathway  Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
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