Human FAM189B Recombinant Protein – Cat# MBS1179840

Protein FAM189B (FAM189B) Human Recombinant Protein

Name: FAM189B Recombinant Protein; Protein FAM189B; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1179840
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1179840

MBS1179840 is a recombinant protein targeting FAM189B. Also known as Recombinant Human Protein FAM189B (FAM189B). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Protein FAM189B (FAM189B), Recombinant Protein

Full Product Name

Recombinant Human Protein FAM189B (FAM189B)

Product Gene Name

FAM189B recombinant protein

Product Synonym Gene Name

FAM189B; C1orf2, COTE1

Product Synonym Names

Recombinant Protein FAM189B (FAM189B); Protein FAM189B; Protein COTE1

Sequence

MMPSPSDSSR SLTSRPSTRG LTHLRLHRPW LQALLTLGLV QVLLGILVVT FSMVASSVTT TESIKRSCPS WAGFSLAFSG VVGIVSWKRP FTLVISFFSL LSVLCVMLSM AGSVLSCKNA QLARDFQQCS LEGKVCVCCP SVPLLRPCPE SGQELKVAPN STCDEARGAL KNLLFSVCGL TICAAIICTL SAIVCCIQIF SLDLVHTLAP ERSVSGPLGP LGCTSPPPAP LLHTMLDLEE FVPPVPPPPY YPPEYTCSSE TDAQSITYNG SMDSPVPLYP TDCPPSYEAV MGLRGDSQAT LFDPQLHDGS CICERVASIV DVSMDSGSLV LSAIGDLPGG SSPSEDSCLL ELQGSVRSVD YVLFRSIQRS RAGYCLSLDC GLRGPFEESP LPRRPPRAAR SYSCSAPEAP PPLGAPTAAR SCHRLEGWPP WVGPCFPELR RRVPRGGGRP AAAPPTRAPT RRFSDSSGSL TPPGHRPPHP ASPPPLLLPR SHSDPGITTS SDTADFRDLY TKVLEEEAAS VSSADTGLCS EACLFRLARC PSPKLLRARS AEKRRPVPTF QKVPLPSGPA PAHSLGDLKG SWPGRGLVTR FLQISRKAPD PSGTGAHGHK QVPRSLWGRP GRESLHLRSC GDLSSSSSLR RLLSGRRLER GTRPHSLSLN GGSRETGL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

71,355 Da

Sequence Positions

1-668

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 1; NC_000001.10 (155216996..155225274, complement). Location: 1q21

3D Structure

ModBase 3D Structure for P81408

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FAM189B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FAM189B. It may not necessarily be applicable to this product.

NCBI GI #

38146116

NCBI GeneID

10712

NCBI Accession #

NP_006580.2

UniProt Primary Accession #

P81408

UniProt Secondary Accession #

Q8IXL3; Q9BR66

UniProt Related Accession #

P81408

GenBank Nucleotide #

NM_006589.2

NCBI Official Full Name

protein FAM189B isoform a

NCBI Official Synonym Full Names

family with sequence similarity 189, member B

NCBI Official Symbol

FAM189B

NCBI Official Synonym Symbols

COTE1; C1orf2

UniProt Protein Name

Protein FAM189B

UniProt Synonym Protein Names

Protein COTE1

Protein Family

Protein

UniProt Gene Name

FAM189B

UniProt Synonym Gene Names

C1orf2; COTE1

UniProt Entry Name

F189B_HUMAN

NCBI Protein Information

protein FAM189B

NCBI Summary for FAM189B

This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

UniProt Comments for FAM189B

FAM189B: This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: integral to membrane

Molecular Function: protein binding; WW domain binding

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with FAM189B recombinant protein

Disease Name	Pubmed Publications
Carcinoma, Hepatocellular Antibodies	>1 publications with FAM189B and Carcinoma, Hepatocellular
Neoplasms Antibodies	>1 publications with FAM189B and Neoplasms
Liver Neoplasms Antibodies	>1 publications with FAM189B and Liver Neoplasms

Organs/Tissues associated with FAM189B recombinant protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1 publications with FAM189B and Liver