Macaca Fascicularis O3FAR1 Recombinant Protein – Cat# MBS1180111

Omega-3 Fatty Acid Receptor 1 (O3FAR1) Macaca Fascicularis Recombinant Protein

Name: O3FAR1 Recombinant Protein; Macaca Fascicularis; MyBioSource
Brand: MyBioSource
SKU: MBS1180111
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1180111

MBS1180111 is a recombinant protein targeting O3FAR1. Also known as Recombinant Macaca fascicularis Omega-3 fatty acid receptor 1 (O3FAR1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Omega-3 fatty acid receptor 1 (O3FAR1), Recombinant Protein

Full Product Name

Recombinant Macaca fascicularis Omega-3 fatty acid receptor 1 (O3FAR1)

Product Gene Name

O3FAR1 recombinant protein

Product Synonym Gene Name

O3FAR1; GPR120

Product Synonym Names

Recombinant Omega-3 fatty acid receptor 1 (O3FAR1); Omega-3 fatty acid receptor 1; G-protein coupled receptor 120

Sequence

MSPECARAAG DAPLRSLEQA NRTRFSFFSD VKGDHRLLLA AVETTVLALI FAVSLLGNVC ALVLVARRRR RGTTACLVLN LFCADLLFIS AIPLVLAVRW TEAWLLGPVA CHLLFYLMTL SGSVTILTLA AVSLERMVCI VHLQRGVRGP GRRARAVLLT LIWGYSAVAA LPLCVFFRVV PQRLPGADQE ISICTLIWPT IAGEISWDVS FVTLNFLVPG LVIVISYSKI LQITKASRKR LTVSLAYSES HQIRVSQQDF RLFRTLFLLM VSFFIMWSPI IITILLILIQ NFKQDLVIWP SLFFWVVAFT FANSALNPIL YNMTLCRNEW KKIFCCFWFP EKGAILTDTS VKRNDLSVIS G

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

40,504 Da

Sequence Positions

1-361

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for C8YUV0

Species

Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of O3FAR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for O3FAR1. It may not necessarily be applicable to this product.

UniProt Primary Accession #

C8YUV0

UniProt Protein Name

Omega-3 fatty acid receptor 1

UniProt Synonym Protein Names

G-protein coupled receptor 120

UniProt Gene Name

O3FAR1

UniProt Synonym Gene Names

GPR120

UniProt Entry Name

O3FA1_MACFA

UniProt Comments for O3FAR1

Function: Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particularly in macrophages and fat cells. The anti-inflammatory effects involved inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect, but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation

By similarity.

Subunit structure: Interacts with ARRB2 following DHA stimulation

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein

By similarity. Note: Colocalized with ARRB2 following docosahexaenoic acid (DHA) treatment

By similarity.

Tissue specificity: Highly expressed in lung and colon. Ref.1

Post-translational modification: Phosphorylated. FFA stimulation facilitates phosphorylation

By similarity.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.