Pig BVES Recombinant Protein – Cat# MBS1180811

Blood Vessel Epicardial Substance (BVES) Pig Recombinant Protein

Name: BVES Recombinant Protein; Blood Vessel Epicardial Substance; Pig; MyBioSource
Brand: MyBioSource
SKU: MBS1180811
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1180811

MBS1180811 is a recombinant protein targeting BVES. Also known as Recombinant Pig Blood vessel epicardial substance (BVES). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Blood vessel epicardial substance (BVES), Recombinant Protein

Full Product Name

Recombinant Pig Blood vessel epicardial substance (BVES)

Product Gene Name

BVES recombinant protein

Product Synonym Gene Name

BVES; POP1, POPDC1

Product Synonym Names

Recombinant Blood vessel epicardial substance (BVES); Blood vessel epicardial substance; Popeye domain-containing protein 1; Popeye protein 1

Sequence

MNYTESSPLA ESTAIGFTPE LGSITPVPSN ETTCENWREI HHLVFHVANV FFAIGLVLPT TLHLHMILLR GMLTIGCTLY IVWATLYRCA LDIMIWNSVF LGINVLHLSY LLYKKRPVKI EKELKGIYQR LFEPLRVPPD LFKRLTGQFC MIQTLKKGQA YAAEDKTSVD DRLSILLKGK MKVSYRGHFL HNIYPCAFID SPEFRSTQMH KGEKFQVTII ADDNCRFLCW SRERLTYFLE SEPFLYEVFR YLIGKDITNK LYSLNDPTLN DKTIKKLDHQ LSLCTQLSML EMRNSIVSTS DSEDGLHQFL RGTSSVSSLY VPSPHQRASA KMKPIEEGVE DDDEVFEPET PNTFKVRQLP

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

41,444 Da

Sequence Positions

1-360

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 1; NC_010443.4 (80647049..80681079, complement). Location: 1; 1

3D Structure

ModBase 3D Structure for B8Q0B2

Species

Sus scrofa (Pig)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of BVES recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BVES. It may not necessarily be applicable to this product.

NCBI GI #

221139746

NCBI GeneID

100153106

NCBI Accession #

NP_001137584.1

UniProt Primary Accession #

B8Q0B2

UniProt Secondary Accession #

B8Q0B1

UniProt Related Accession #

B8Q0B2

GenBank Nucleotide #

NM_001144112.1

NCBI Official Full Name

blood vessel epicardial substance

NCBI Official Symbol

BVES

NCBI Official Synonym Symbols

POP1; POPDC1

UniProt Protein Name

Blood vessel epicardial substance

UniProt Synonym Protein Names

Popeye domain-containing protein 1

Protein Family

Blood vessel epicardial substance

UniProt Gene Name

BVES

UniProt Synonym Gene Names

POP1; POPDC1; Popeye protein 1

UniProt Entry Name

POPD1_PIG

NCBI Protein Information

blood vessel epicardial substance; Popeye protein 1; Popeye domain-containing protein 1; popeye domain containing protein 1

UniProt Comments for BVES

Function: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca2+-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading

By similarity.

Subunit structure: Homodimer. Homodimerization requires the C-terminus cytoplasmic region. Interacts (via the C-terminus cytoplasmic tail) with TJP1. Interacts (via the C-terminus cytoplasmic tail) with ARHGEF25/GEFT (via the DH domain). Interacts (via the C-terminus cytoplasmic tail) with VAMP3

By similarity.

Subcellular location: Lateral cell membrane

By similarity. Cell junction › tight junction

By similarity. Membrane; Multi-pass membrane protein

Potential. Note: Its movement from the cytoplasm to membrane is an early event occurring concurrently with cell-cell contact. Detected at cell-cell contact but never observed at the free surface of epithelial cells. Colocalizes in epithelial cells with OCLN and TJP1 in an apical-lateral position within the z axis. Colocalizes with VAMP3 at the cell-cell contact in cardiac and skeletal muscle

By similarity.

Sequence similarities: Belongs to the popeye family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with BVES recombinant protein

Disease Name	Pubmed Publications
Heart Diseases Antibodies	>5 publications with BVES and Heart Diseases
Central Nervous System Neoplasms Antibodies	>1 publications with BVES and Central Nervous System Neoplasms
Uveal Neoplasms Antibodies	>1 publications with BVES and Uveal Neoplasms
Fibrosis Antibodies	>1 publications with BVES and Fibrosis

Organs/Tissues associated with BVES recombinant protein

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>18 publications with BVES and Heart
Embryonic Tissue Antibodies	>14 publications with BVES and Embryonic Tissue
Ovary Antibodies	>1 publications with BVES and Ovary