Schizosaccharomyces Pombe tim40 Recombinant Protein – Cat# MBS1185976

Mitochondrial Intermembrane Space Import and Assembly Protein 40 (Mia40) (tim40) Schizosaccharomyces Pombe Recombinant Protein

Name: tim40 Recombinant Protein; Schizosaccharomyces Pombe; MyBioSource
Brand: MyBioSource
SKU: MBS1185976
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1185976

MBS1185976 is a recombinant protein targeting tim40. Also known as Recombinant Schizosaccharomyces pombe Mitochondrial intermembrane space import and assembly protein 40 (mia40). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Mitochondrial intermembrane space import and assembly protein 40 (mia40) (tim40), Recombinant Protein

Full Product Name

Recombinant Schizosaccharomyces pombe Mitochondrial intermembrane space import and assembly protein 40 (mia40)

Product Gene Name

tim40 recombinant protein

Product Synonym Gene Name

mia40; tim40; SPAC57A10.11c

Product Synonym Names

Recombinant Mitochondrial intermembrane space import and assembly protein 40 (mia40); Mitochondrial intermembrane space import and assembly protein 40; Mitochondrial import inner membrane translocase TIM40

Sequence

AASLTAGYLL GKNTSNASSS QDNDHPVVGE HVHTETQSYN EPYMQRHRIE DAIEKKMTSE TQPSTDEKGR KVSATENSAP KKTDKEKSSG ETAGNILREQ IATGKDDDEY ARKFEEVEEE SSEESAFNPD TGEINWDCPC LGGMAHGPCG EEFKAAFSCF VYSKSEPKGM ECLDKFQAMQ ACFQKHPEIY QDMVGESEEE DAETNEKPST TSDENNQPQS PPSDNASNPE EDVMNMEKEI VNLTPMSVIK EI

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

34,915 Da

Sequence Positions

62-313

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: I; NC_003424.3 (1383532..1385287, complement). Location: chromosome: I

3D Structure

ModBase 3D Structure for P87059

Species

Schizosaccharomyces pombe (strain 972 / 24843) (Fission yeast)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of tim40 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for tim40. It may not necessarily be applicable to this product.

NCBI GI #

19114228

NCBI GeneID

2542760

NCBI Accession #

NP_593316.1

UniProt Primary Accession #

P87059

UniProt Related Accession #

P87059

GenBank Nucleotide #

NM_001018747.2

NCBI Official Full Name

TIM22 inner membrane protein import complex subunit Tim40 (predicted)

NCBI Official Symbol

tim40

UniProt Protein Name

Mitochondrial intermembrane space import and assembly protein 40

UniProt Synonym Protein Names

Mitochondrial import inner membrane translocase TIM40

UniProt Gene Name

mia40

UniProt Synonym Gene Names

tim40

UniProt Entry Name

MIA40_SCHPO

NCBI Protein Information

TIM22 inner membrane protein import complex subunit Tim40 (predicted)

UniProt Comments for tim40

Function: Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS

By similarity.

Cofactor: Copper or zinc

By similarity.

Subunit structure: Monomer

By similarity.

Subcellular location: Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side

By similarity.

Domain: The CHCH domain contains a conserved twin Cys-X(9)-Cys motif which is required for import and stability of MIA40 in mitochondria

By similarity.

Sequence similarities: Contains 1 CHCH domain.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with tim40 recombinant protein

Reference Product	PubMed Publications
erv1 recombinant protein	>26 publications with tim40 and erv1
tim9 recombinant protein	>5 publications with tim40 and tim9
tim13 recombinant protein	>3 publications with tim40 and tim13
cox17 recombinant protein	>2 publications with tim40 and cox17
cox19 recombinant protein	>1 publications with tim40 and cox19

Pathways associated with tim40 recombinant protein

Products by Pathway	Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Mitochondrial Protein Import Pathway antibodies	Mitochondrial Protein Import Pathway Diagram