Drosophila Melanogaster cyc Recombinant Protein – Cat# MBS1189079

Protein Cycle (cyc) Drosophila Melanogaster Recombinant Protein

Name: cyc Recombinant Protein; Protein Cycle; Drosophila Melanogaster; MyBioSource
Brand: MyBioSource
SKU: MBS1189079
Price: 1155 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1189079

MBS1189079 is a recombinant protein targeting cyc. Also known as Recombinant Drosophila melanogaster Protein cycle (cyc). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1155 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Protein cycle (cyc), Recombinant Protein

Full Product Name

Recombinant Drosophila melanogaster Protein cycle (cyc)

Product Gene Name

cyc recombinant protein

Sequence

MEVQEFCENM EEIEDENYDE EKSARTSDEN RKQNHSEIEK RRRDKMNTYI NELSSMIPMC FAMQRKLDKL TVLRMAVQHL RGIRGSGSLH PFNGSDYRPS FLSDQELKMI ILQASEGFLF VVGCDRGRIL YVSDSVSSVL NSTQADLLGQ SWFDVLHPKD IGKVKEQLSS LEQCPRERLI DAKTMLPVKT DVPQSLCRLC PGARRSFFCR MKLRTASNNQ IKEESDTSSS SRSSTKRKSR LTTGHKYRVI QCTGYLKSWT PIKDEDQDAD SDEQTTNLSC LVAIGRIPPN VRNSTVPASL DNHPNIRHVL FISRHSGEGK FLFIDQRATL VIGFLPQEIL GTSFYEYFHN EDIAALMESH KMVMQVPEKV TTQVYRFRCK DNSYIQLQSE WRAFKNPWTS EIDYIIAKNS VFL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

47,569 Da

Sequence Positions

1-413, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O61734

Species

Drosophila melanogaster (Fruit fly)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of cyc recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for cyc. It may not necessarily be applicable to this product.

NCBI GI #

24667005

NCBI GeneID

40162

NCBI Accession #

NP_524168.2

UniProt Primary Accession #

O61734

UniProt Secondary Accession #

O76344; Q1LZ29; Q540W7; Q9VW44

UniProt Related Accession #

O61734

GenBank Nucleotide #

NM_079444.3

NCBI Official Full Name

cycle

NCBI Official Synonym Full Names

cycle

NCBI Official Symbol

cyc

NCBI Official Synonym Symbols

bHLHe7; bMAL1; Bmal1; BMAL1; CG8727; Cyc; CYC; Cycle; CYCLE; dBma1; dbmal; dBmal; dBMAL; dbmal1; dBMAL1; dCYC; DmelCG8727; Mop3; MOP3; TGO_CYC

UniProt Protein Name

Protein cycle

UniProt Synonym Protein Names

Brain and muscle ARNT-like 1; BMAL1; MOP3

Protein Family

Cytochrome

UniProt Gene Name

cyc

UniProt Synonym Gene Names

BMAL1

NCBI Protein Information

CG8727 gene product from transcript CG8727-RA

UniProt Comments for cyc

Putative transcription factor involved in the generation of biological rhythms. Activates cycling transcription of Period (PER) and Timeless (TIM) by binding to the E-box (5'-CACGTG-3') present in their promoters.

Research Articles on cyc

1. Here we demonstrate that the transcription factor CLOCKWORK ORANGE (CWO) antagonizes CLK-CYC E-box binding, thus enhancing the removal of CLK-CYC from E-boxes to maintain transcriptional repression. This process requires PER, which suggests that PER-TIM and CWO cooperate to maintain a transcriptionally repressed state by removing CLK-CYC from E-boxes

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with cyc recombinant protein

Products by Pathway	Pathway Diagram
BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway antibodies	BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway Diagram
Circadian Clock Pathway antibodies	Circadian Clock Pathway Diagram
Circadian Rhythm - Fly Pathway antibodies	Circadian Rhythm - Fly Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
PPARA Activates Gene Expression Pathway antibodies	PPARA Activates Gene Expression Pathway Diagram
REV-ERBA Represses Gene Expression Pathway antibodies	REV-ERBA Represses Gene Expression Pathway Diagram
RORA Activates Circadian Gene Expression Pathway antibodies	RORA Activates Circadian Gene Expression Pathway Diagram
Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies	Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram

Diseases associated with cyc recombinant protein

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>128 publications with cyc and Kidney Diseases
Eye Diseases Antibodies	>73 publications with cyc and Eye Diseases
Inflammation Antibodies	>30 publications with cyc and Inflammation
Heart Diseases Antibodies	>30 publications with cyc and Heart Diseases
Necrosis Antibodies	>25 publications with cyc and Necrosis
Leukemia Antibodies	>24 publications with cyc and Leukemia
Genital Diseases, Female Antibodies	>21 publications with cyc and Genital Diseases, Female
Gonadal Disorders Antibodies	>21 publications with cyc and Gonadal Disorders
Glucose Metabolism Disorders Antibodies	>8 publications with cyc and Glucose Metabolism Disorders
Cysts Antibodies	>6 publications with cyc and Cysts

Organs/Tissues associated with cyc recombinant protein

Organ/Tissue Name	Pubmed Publications
Head Antibodies	>39 publications with cyc and Head
Ovary Antibodies	>31 publications with cyc and Ovary
Gonad Antibodies	>29 publications with cyc and Gonad
Embryonic Tissue Antibodies	>15 publications with cyc and Embryonic Tissue
Fat Body Antibodies	>9 publications with cyc and Fat Body
Whole Body Antibodies	>6 publications with cyc and Whole Body