Saccharomyces Cerevisiae NPL6 Recombinant Protein – Cat# MBS1190886

Chromatin Structure-Remodeling Complex Subunit RSC7 (NPL6) Saccharomyces Cerevisiae Recombinant Protein

Name: NPL6 Recombinant Protein; Saccharomyces Cerevisiae; MyBioSource
Brand: MyBioSource
SKU: MBS1190886
Price: 1195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1190886

MBS1190886 is a recombinant protein targeting NPL6. Also known as Recombinant Saccharomyces cerevisiae Chromatin structure-remodeling complex subunit RSC7 (NPL6). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1195 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Chromatin structure-remodeling complex subunit RSC7 (NPL6), Recombinant Protein

Full Product Name

Recombinant Saccharomyces cerevisiae Chromatin structure-remodeling complex subunit RSC7 (NPL6)

Product Gene Name

NPL6 recombinant protein

Sequence

MSDSEGGLAS EVEHEKRSRS TSNRPNYAID TEDLDIDEND ENEDDDYREE EANEGVNEEE ISDEEEQINK SGRNKRRHVD EEEDLSEDKG VTRSRNRSKF KKPVFPGIDD AEENLNPLKV VNEEYVLPDD PEGETKITAD GDLLGGREFL VRTFTLTEKG NRKFMLATEP ARIVGFRDSY LFFQTHPNLY KFILNQTQKN DLIDRGVLPY SYRNRQIALV TARGVFKEFG AKIIRGGKHI TDDYYASELR TKGNVIEGKL AGDPIDKSAR ALETMMYPAS ENGINPAKNQ VEFFEHRPHG HMSNSNIIAS GSKLSSTNWL YQHSAACSRF NSDLFYDRVK VLLVDQQGLR DAYTNILHIP ESTQSTTVLG WRRSKNDSPS DTSIVYETVI HDNDLNKPKT GLSEIPKEIY EDVVDEDVLR AITEQQNFEK CNEYI

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

49,651 Da

Sequence Positions

1-435, full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P32832

Species

Saccharomyces cerevisiae (strain 204508 / S288c) (Baker's yeast)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NPL6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NPL6. It may not necessarily be applicable to this product.

NCBI GI #

6323738

NCBI GeneID

855116

NCBI Accession #

NP_013809.1

UniProt Primary Accession #

P32832

UniProt Secondary Accession #

D6VZR4

UniProt Related Accession #

P32832

GenBank Nucleotide #

NM_001182591.1

NCBI Official Full Name

Npl6p

NCBI Official Symbol

NPL6

NCBI Official Synonym Symbols

RSC7

UniProt Protein Name

Chromatin structure-remodeling complex subunit RSC7

UniProt Synonym Protein Names

Nuclear protein localization protein 6; Remodel the structure of chromatin complex subunit 7

Protein Family

Chromatin structure-remodeling complex

UniProt Gene Name

NPL6

UniProt Synonym Gene Names

RSC7

NCBI Protein Information

Npl6p

UniProt Comments for NPL6

Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. Together with HTL1, LDB7, RSC3, RSC30 components, defines a fungal-specific module within the RSC complex that plays a role in many cellular functions including the maintenance of cell wall integrity. Acidic protein important for nuclear protein localization.

Research Articles on NPL6

1. The data support a model in which the human ACF anf yeast RSC remodeling enzymes move nucleosomes to new locations by a general sequence-independent mechanism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NPL6 recombinant protein

Reference Product	PubMed Publications
RSC30 recombinant protein	>1 publications with NPL6 and RSC30