Vipera Ammodytes Ammodytes SVMP Recombinant Protein – Cat# MBS1193426

Zinc Metalloproteinase-Disintegrin Ammodytagin (SVMP) Vipera Ammodytes Ammodytes Recombinant Protein

Name: SVMP Recombinant Protein; Vipera Ammodytes Ammodytes; MyBioSource
Brand: MyBioSource
SKU: MBS1193426
Price: 820 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1193426

MBS1193426 is a recombinant protein targeting SVMP. Also known as Recombinant Vipera ammodytes ammodytes Zinc metalloproteinase-disintegrin ammodytagin. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$820 / 0.05 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Zinc metalloproteinase-disintegrin ammodytagin (SVMP), Recombinant Protein

Full Product Name

Recombinant Vipera ammodytes ammodytes Zinc metalloproteinase-disintegrin ammodytagin

Product Gene Name

SVMP recombinant protein

Product Synonym Names

Recombinant Zinc metalloproteinase-disintegrin ammodytagin; Zinc metalloproteinase-disintegrin ammodytagin EC= 3.4.24.-; Ammodytagin

Sequence

KSAAXVTLDL FGDWRAKRHD NAQLLTGINL NGQTLGIAFM SKXSVGLIQD YXKSYLLVAS VMAELGHNLG MEHDDGNXIX PAKXIDNKPL RTDIVSPAVX GNYFVELTPG SQCADGVCCD QCRKAGVTVA PDLXFDYNQL GTEDKFTHSP DDPDYGMVDL GTKCADGKVC NSNRQXVDVN TAY

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

19,879 Da

Sequence Positions

1-183aa; full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for B3A0S6

Species

Vipera ammodytes ammodytes (Western sand viper)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SVMP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SVMP. It may not necessarily be applicable to this product.

UniProt Primary Accession #

B3A0S6

UniProt Secondary Accession #

B3A0S6

UniProt Protein Name

Zinc metalloproteinase-disintegrin ammodytagin

UniProt Synonym Protein Names

Snake venom metalloproteinase

UniProt Gene Name

SVMP

UniProt Synonym Gene Names

SVMP

UniProt Entry Name

VM3A_VIPAA

UniProt Comments for SVMP

Function: Snake venom zinc metalloprotease that has fibrinogenolytic and hemorrhagic activities in mouse and rats. Hydrolyzes the Aalpha-chain (FGA) and more slowly the Bbeta-chain of fibrinogen (FGB), without affecting the gamma-chain. Its hemorrhagic activity results of its involvement in cleavage of basal membrane components (nidogen and fibronectin but not laminin) and depletion of fibrinogen, prothrombin (F2) and factor X (F10) in blood circulation. Also possess potent azocaseinolytic activity and cleaves insulin B-chain, hydrolyzing it at positions Gln(4)-His5, His(10)-Leu(11) and Tyr(16)-Leu(17). Ref.1

Cofactor: Binds 1 calcium ion

By similarity.Binds 1 zinc ion

By similarity.

Enzyme regulation: Inhibited by EDTA, DTT and zinc ions. Partially inhibited by L-cysteine. Not inhibited by 2-propanol or PMSF. Activity is enhanced by calcium or magnesium ions. Ref.1

Subunit structure: Heterodimer; disulfide-linked. Ref.1

Subcellular location: Secreted.

Tissue specificity: Expressed by the venom gland. Ref.1

Post-translational modification: The N-terminus is blocked.N-glycosylated. Ref.1

Miscellaneous: The hemorrhagic activity of the whole venom is completely neutralized by an antiserum against this metalloproteinase (Ref.1).

Sequence similarities: Belongs to the venom metalloproteinase family. P-III subfamily.Contains 1 disintegrin domain.Contains 1 peptidase M12B domain.

Mass spectrometry: Molecular mass is 108000 Da . Determined by MALDI. Monomer. Ref.1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.