Rat HOMER2 Recombinant Protein – Cat# MBS1197017

Homer Protein Homolog 2 (HOMER2) Rat Recombinant Protein

Name: HOMER2 Recombinant Protein; Homer Protein Homolog 2; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS1197017
Price: 1070 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1197017

This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein may be involved in cell growth. Four transcript variants encoding distinct isoforms… More details

$1070 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Homer protein homolog 2 (Homer2), Recombinant Protein

Full Product Name

Recombinant Rat Homer protein homolog 2 (Homer2)

Product Gene Name

Homer2 recombinant protein

Sequence

MGEQPIFTTR AHVFQIDPST KKNWVPASKQ AVTVSYFYDV TRNSYRIISV DGAKVIINST ITPNMTFTKT SQKFGQWADS RANTVFGLGF SSEQQLTKFA EKFQEVREAA RLARDKSQEK IETSSNHSQE SGCETPSSTQ ASSVNGTDDE KASHASPADT HLKSENDKLK IALTQSAANV KKWEIELQTL RESNARLTTA LQESAASVEQ WKRQFSICRD ENDRLRSKIE ELEEQCGEIN REKEKNTQLK RRIEELESEV REKEMELKDL RKQSEIIPQL MSECEYVSEK LEAAERDNQN LEDKVRSLKT DIEESKYRQR HLKGELKSFL EVLDGKIDDL HDFRRGLSKL GTDN

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

39,456 Da

Sequence Positions

1-354, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O88801

Species

Rat

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Homer2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Homer2 purchase

MBS1197017 is a recombinant protein targeting Homer2. Also known as Recombinant Rat Homer protein homolog 2 (Homer2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Homer2. It may not necessarily be applicable to this product.

NCBI GI #

16758006

NCBI GeneID

29547

NCBI Accession #

NP_445761.1

UniProt Primary Accession #

O88801

UniProt Secondary Accession #

O88802

UniProt Related Accession #

O88801

GenBank Nucleotide #

NM_053309.1

NCBI Official Full Name

homer protein homolog 2

NCBI Official Synonym Full Names

homer scaffolding protein 2

NCBI Official Symbol

Homer2

NCBI Official Synonym Symbols

Vesl-2

UniProt Protein Name

Homer protein homolog 2

UniProt Synonym Protein Names

Cupidin; VASP/Ena-related gene up-regulated during seizure and LTP 2; Vesl-2

Protein Family

Homer protein

UniProt Gene Name

Homer2

UniProt Synonym Gene Names

Vesl2; Homer-2; Vesl-2

NCBI Protein Information

homer protein homolog 2

NCBI Summary for Homer2

binds metabotropic glutamate receptors mGluR1 and mGluR5 [RGD, Feb 2006]

UniProt Comments for Homer2

Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. Required for normal hearing ().

Research Articles on Homer2

1. In alcohol-preferring rats, Homer2b expression in the nucleus accumbens regulates alcohol consumption.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Homer2 recombinant protein

Reference Product	PubMed Publications
Homer3 recombinant protein	>6 publications with Homer2 and Homer3
Ryr1 recombinant protein	>2 publications with Homer2 and Ryr1
Grm5 recombinant protein	>1 publications with Homer2 and Grm5

Pathways associated with Homer2 recombinant protein

Products by Pathway	Pathway Diagram
FoxO Signaling Pathway antibodies	FoxO Signaling Pathway Diagram
Glutamatergic Synapse Pathway antibodies	Glutamatergic Synapse Pathway Diagram
Glutamatergic Synapse Pathway antibodies	Glutamatergic Synapse Pathway Diagram

Diseases associated with Homer2 recombinant protein

Disease Name	Pubmed Publications
Cocaine-Related Disorders Antibodies	>5 publications with Homer2 and Cocaine-Related Disorders
Nervous System Diseases Antibodies	>4 publications with Homer2 and Nervous System Diseases
Pain Antibodies	>2 publications with Homer2 and Pain
Abnormalities, Drug-Induced Antibodies	>1 publications with Homer2 and Abnormalities, Drug-Induced
Learning Disorders Antibodies	>1 publications with Homer2 and Learning Disorders
Disease Models, Animal Antibodies	>1 publications with Homer2 and Disease Models, Animal
Cognition Disorders Antibodies	>1 publications with Homer2 and Cognition Disorders

Organs/Tissues associated with Homer2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>1 publications with Homer2 and Heart