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Mitochondrial Inner Membrane I-AAA Protease Supercomplex Subunit MGR1 (MGR1) Saccharomyces Cerevisiae Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1198420

MBS1198420 is a recombinant protein targeting MGR1. Also known as Recombinant Saccharomyces cerevisiae Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1 (MGR1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1 (MGR1), Recombinant Protein
Full Product Name
Recombinant Saccharomyces cerevisiae Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1 (MGR1)
Product Gene Name
MGR1 recombinant protein
Product Synonym Gene Name
MGR1
Product Synonym Names
Recombinant Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1 (MGR1); Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1; Mitochondrial genome-required protein 1
Sequence
MAVFTPPSGN SNSTDHTHTQ DDHDKDDNDI KKFYIRPSLG LKLWGPLVPA PDNLPGLYTL ITIQSAVGFF ALWRLRRLYK LPPPRRIATG THSDLSFGEL PSEMIVNGKT KIKKDIADFP TLNRFSTTHG DIVLAPPPII PRQSRFVSVR KLLWGLFGSL LLSQSLLELT RLNFLKYDPW CDEMKSVRDK KFFNNIVKYY HEGIDPTKIK VKDAMNGTPL STNIPEVKQS VALARAQVEA QNPIIKWFGP LEYKPMSFNE YLNRMEFHLD MFEFFQNKRN IRENSIELIN SISHNPQSSS TGLEGLSESK KLHLQNVEKR LHFLASSGDS ISAPVKKRSS TTLSRGVILP HDTKGPQDID LDTIRSLYDP WMTLALETSL SIKFIPTTMP SHTKTPTSTD QPLPGPTPKA LTNEKTH
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
47,156 Da
Sequence Positions
1-417
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: III; NC_001135.5 (47111..48364, complement). Location: chromosome: III
3D Structure
ModBase 3D Structure for P25573
Species
Saccharomyces cerevisiae (strain 204508 / S288c) (Baker's yeast)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MGR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MGR1. It may not necessarily be applicable to this product.

NCBI GI #
6319805
NCBI GeneID
850313
NCBI Accession #
NP_009886.1
UniProt Primary Accession #
P25573
UniProt Secondary Accession #
D6VQX2
UniProt Related Accession #
P25573
GenBank Nucleotide #
NM_001178689.1
NCBI Official Full Name
Mgr1p
NCBI Official Symbol
MGR1
UniProt Protein Name
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1
UniProt Synonym Protein Names
Mitochondrial genome-required protein 1
Protein Family
Mitochondrial genome required protein
UniProt Gene Name
MGR1
UniProt Entry Name
MGR1_YEAST
NCBI Protein Information
Mgr1p

UniProt Comments for MGR1

Function: Component of the mitochondrial inner membrane i-AAA protease supercomplex required for mitochondrial inner membrane protein turnover. Together with MGR3, functions in an adapter complex that targets substrates to the i-AAA protease for degradation. Required for growth of cells lacking the mitochondrial genome. Ref.7 Ref.8

Subunit structure: Component of the mitochondrial inner membrane i-AAA protease supercomplex composed of MGR1, MGR3 and YME1. With MGR3, forms a subcomplex that binds to YME1 and to substrates to facilitate proteolysis. Interacts directly with YME1. Ref.7 Ref.8

Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein Ref.4 Ref.6 Ref.7.

Miscellaneous: Present with 3410 molecules/cell in log phase SD medium.

Sequence similarities: Belongs to the MGR1 family.
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Research Articles on MGR1

1. Results suggest that Mgr3p and Mgr1p function in an adaptor complex that targets substrates to the i-AAA protease for degradation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MGR1 recombinant protein

 Reference Product  PubMed Publications
 YME1 recombinant protein  >4 publications with MGR1 and YME1
 MGR2 recombinant protein  >3 publications with MGR1 and MGR2
 COX18 recombinant protein  >2 publications with MGR1 and COX18
 COX20 recombinant protein  >1 publications with MGR1 and COX20
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