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ETV3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS120062

Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity{EC1}. [NCBI Entrez Gene Summary] More details

$575 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ETV3, Monoclonal Antibody
Full Product Name
Mouse monoclonal antibody Anti-Human ETV3
Product Gene Name
Product Synonym Names
ets variant gene 3; PE1; METS; bA110J1.4; PE-1
Clonality
Monoclonal
Isotype
IgG1
Clone Number
ETV3F4D10
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Molecular Weight
16,943 Da
OMIM
164873
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Applications Tested/Suitable for anti-ETV3 antibody
Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB)

Quality Control of anti-ETV3 antibody

Western blot analysis of immunized recombinant protein, using anti-ETV3 monoclonal antibody.
Mouse Anti-ETV3 Monoclonal Antibody – Cat# MBS120062

Quality Control #2 of anti-ETV3 antibody

Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Mouse Anti-ETV3 Monoclonal Antibody, Quality Control #2 – Cat# MBS120062

Western Blot (WB) of anti-ETV3 antibody

Detection of human ETV3 by Western blot.

Samples: Whole cell lysate (50 ug) from HeLa cells. [Lot No. ETV3F4D10-1]

Predicted molecular weight: 16 kDa
Mouse Anti-ETV3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS120062

Immunocytochemistry (ICC) of anti-ETV3 antibody

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-ETV3 mAb. [Lot No. ETV3F4D10-1]
Mouse Anti-ETV3 Monoclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS120062

Other Notes

Small volumes of anti-ETV3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ETV3 purchase

MBS120062 is an antibody targeting ETV3. Also known as Mouse monoclonal antibody Anti-Human ETV3. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ETV3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens ets variant 3, mRNA
NCBI Official Synonym Full Names
ets variant 3
NCBI Official Symbol
ETV3
NCBI Official Synonym Symbols
PE1; METS; PE-1; bA110J1.4
UniProt Protein Name
ETS translocation variant 3
UniProt Synonym Protein Names
ETS domain transcriptional repressor PE1; PE-1; Mitogenic Ets transcriptional suppressor
Protein Family
UniProt Gene Name
ETV3
UniProt Entry Name
ETV3_HUMAN
NCBI Protein Information
ETS translocation variant 3; ETS domain transcriptional repressor PE1; ets variant gene 3, ETS family transcriptional repressor; mitogenic Ets transcriptional suppressor

UniProt Comments for ETV3

ETV3: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity. Belongs to the ETS family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1q21-q23

Cellular Component: transcriptional repressor complex; nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ETV3 antibody

 Reference Product  PubMed Publications
 DDX20 antibody  >1 publications with ETV3 and DDX20

Organs/Tissues associated with anti-ETV3 antibody

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