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CHD6 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS120148

Chromosomal DNA of eukaryotic cells is compacted by nuclear proteins to form chromatin, an organized nucleoprotein structure that can inhibit gene expression. Several multisubunit protein complexes exist to remodel the chromatin to allow patterns of cell… More details

$575 / 0.1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
CHD6, Monoclonal Antibody
Full Product Name
Mouse monoclonal antibody Anti-Human CHD6
Product Gene Name
Product Synonym Names
Homo sapiens chromodomain helicase DNA binding protein 6 (CHD6); CHD5; RIGB; KIAA1335
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2174C2a
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Molecular Weight
94,609 Da
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Applications Tested/Suitable for anti-CHD6 antibody
Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB)

Quality Control of anti-CHD6 antibody

Left: Western blot analysis of immunized recombinant protein, using anti-CHD6 monoclonal antibody.
Mouse Anti-CHD6 Monoclonal Antibody – Cat# MBS120148

Western Blot (WB) of anti-CHD6 antibody

Detection of human CHD6 by Western blot.

Samples: Whole cell lysate (25 ug) from HeLa cells. [Lot No. 2174C2a-1]

Predicted molecular weight: 305 kDa
Mouse Anti-CHD6 Monoclonal Antibody, Western Blot (WB) – Cat# MBS120148

Immunocytochemistry (ICC) of anti-CHD6 antibody

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-CHD6 mAb. [Lot No. 2174C2a-1]
Mouse Anti-CHD6 Monoclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS120148

Other Notes

Small volumes of anti-CHD6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHD6 purchase

MBS120148 is an antibody targeting CHD6. Also known as Mouse monoclonal antibody Anti-Human CHD6. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CHD6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens chromodomain helicase DNA binding protein 6 (CHD6), mRNA
NCBI Official Synonym Full Names
chromodomain helicase DNA binding protein 6
NCBI Official Symbol
CHD6
NCBI Official Synonym Symbols
CHD5; RIGB; CHD-6
UniProt Protein Name
Chromodomain-helicase-DNA-binding protein 6
UniProt Synonym Protein Names
ATP-dependent helicase CHD6; Radiation-induced gene B protein
UniProt Gene Name
CHD6
UniProt Entry Name
CHD6_HUMAN
NCBI Protein Information
chromodomain-helicase-DNA-binding protein 6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SNF2 N-terminal domain-containing protein; radiation-induced gene B protein

NCBI Summary for CHD6

This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]
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UniProt Comments for CHD6

CHD-6: may be a transcriptional regulator. Three alternatively spliced isoforms have been described.

Protein type: Helicase; DNA-binding; EC 3.6.4.12

Chromosomal Location of Human Ortholog: 20q12

Cellular Component: nucleoplasm; DNA-directed RNA polymerase II, core complex

Molecular Function: DNA-dependent ATPase activity; DNA binding; ATP-dependent helicase activity; chromatin binding; ATP binding

Biological Process: transcription, DNA-dependent; chromatin modification
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Research Articles on CHD6

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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