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GTF3C2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS120236

Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing… More details

$575 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GTF3C2, Monoclonal Antibody
Full Product Name
Mouse monoclonal antibody Anti-Human GTF3C2
Product Gene Name
Product Synonym Names
Homo sapiens general transcription factor IIIC, polypeptide 2, beta 110kDa (GTF3C2), transcript variant 1; KIAA0011; TFIIIC110; TFIIIC-BETA
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2395C2a
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Molecular Weight
64,003 Da
OMIM
604883
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Applications Tested/Suitable for anti-GTF3C2 antibody
Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB)

Quality Control of anti-GTF3C2 antibody

Western blot analysis of immunized recombinant protein, using anti-GTF3C2 monoclonal antibody.
Mouse Anti-GTF3C2 Monoclonal Antibody – Cat# MBS120236

Quality Control #2 of anti-GTF3C2 antibody

Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Mouse Anti-GTF3C2 Monoclonal Antibody, Quality Control #2 – Cat# MBS120236

Western Blot (WB) of anti-GTF3C2 antibody

Detection of human GTF3C2 by Western blot.

Samples: Whole cell lysate (25 ug) from HeLa cells. [Lot No. 2395C2a-1]

Predicted molecular weight: 100 kDa
Mouse Anti-GTF3C2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS120236

Immunocytochemistry (ICC) of anti-GTF3C2 antibody

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-GTF3C2 mAb. [Lot No. 2395C2a-1]
Mouse Anti-GTF3C2 Monoclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS120236

Other Notes

Small volumes of anti-GTF3C2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GTF3C2 purchase

MBS120236 is an antibody targeting GTF3C2. Also known as Mouse monoclonal antibody Anti-Human GTF3C2. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF3C2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens general transcription factor IIIC, polypeptide 2, beta 110kDa (GTF3C2), transcript variant 1, mRNA
NCBI Official Synonym Full Names
general transcription factor IIIC, polypeptide 2, beta 110kDa
NCBI Official Symbol
GTF3C2
NCBI Official Synonym Symbols
TFIIIC110; TFIIIC-BETA
UniProt Protein Name
General transcription factor 3C polypeptide 2
UniProt Synonym Protein Names
TF3C-beta; Transcription factor IIIC 110 kDa subunit; TFIIIC 110 kDa subunit; TFIIIC110; Transcription factor IIIC subunit beta
UniProt Gene Name
GTF3C2
UniProt Entry Name
TF3C2_HUMAN
NCBI Protein Information
general transcription factor 3C polypeptide 2; TF3C-beta; TFIIIC 110 kDa subunit; transcription factor IIIC 110 kDa subunit; transcription factor IIIC subunit beta

UniProt Comments for GTF3C2

GTF3C2: Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: nucleoplasm; transcription factor TFIIIC complex

Molecular Function: DNA binding

Biological Process: transcription from RNA polymerase III promoter; transcription, DNA-dependent; 5S class rRNA transcription; gene expression; tRNA transcription from RNA polymerase III promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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