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LSM10 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS120272

MBS120272 is an antibody targeting LSM10. Also known as Mouse monoclonal antibody Anti-Human LSM10. Reactive in Human. Host: Mouse. Binds specifically to U7 snRNA. [UniProtKB Function] More details

$575 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LSM10, Monoclonal Antibody
Full Product Name
Mouse monoclonal antibody Anti-Human LSM10
Product Gene Name
Product Synonym Names
Homo sapiens LSM10, U7 small nuclear RNA associated (LSM10); MST074; MSTP074; MGC15749
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
2522C1a
Host
Mouse
Species Reactivity
Human
Form/Format
Mouse monoclonal anti-human LSM10 antibody in PBS (3.0 mM KCI, 1.5 mM KH2PO4, 140 mM NaCl, 8.0 mM Na2HPO4(pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide.
Concentration
100 ug/ml (1.0 ml) (lot specific)
Preparation and Storage
Store at 2-8°C for up to 1 year.
We recommend storing at -20°C for long term storage.
Avoid repeat freezing and thawing cycles.
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Immunogen
Recombinant
Sterility
Filtered through a 0.22 um membrane.
Disposal
This antibody solution contains sodium azide as a preservative. There is a potential hazard that NaN3 reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water.
Applications Tested/Suitable for anti-LSM10 antibody
Dot Blot (DB), Immunocytochemistry (ICC)
Application Notes for anti-LSM10 antibody
ICC: 2-100 ug/ml

Quality Control of anti-LSM10 antibody

Western blot analysis of immunized recombinant protein, using anti-LSM10 monoclonal antibody.
Mouse Anti-LSM10 Monoclonal Antibody – Cat# MBS120272

Quality Control #2 of anti-LSM10 antibody

Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Mouse Anti-LSM10 Monoclonal Antibody, Quality Control #2 – Cat# MBS120272

Immunocytochemistry (ICC) of anti-LSM10 antibody

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-LSM10 mAb. [Lot No.2522C1a-1]
Mouse Anti-LSM10 Monoclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS120272

Other Notes

Small volumes of anti-LSM10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LSM10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens LSM10, U7 small nuclear RNA associated (LSM10), mRNA
NCBI Official Synonym Full Names
LSM10, U7 small nuclear RNA associated
NCBI Official Symbol
LSM10
NCBI Official Synonym Symbols
MST074; MSTP074
UniProt Protein Name
U7 snRNA-associated Sm-like protein LSm10
UniProt Gene Name
LSM10
UniProt Entry Name
LSM10_HUMAN
NCBI Protein Information
U7 snRNA-associated Sm-like protein LSm10; U7 snRNP-specific Sm-like protein LSM10

UniProt Comments for LSM10

LSM10: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. Belongs to the snRNP Sm proteins family.

Chromosomal Location of Human Ortholog: 1p34.3

Cellular Component: nucleoplasm; Cajal body; nucleus

Molecular Function: protein binding

Biological Process: transcription from RNA polymerase II promoter; RNA splicing; histone mRNA metabolic process; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-LSM10 antibody

Organs/Tissues associated with anti-LSM10 antibody

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