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FBXL4 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS120280

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
FBXL4, Monoclonal Antibody
Full Product Name
Mouse monoclonal antibody Anti-Human FBXL4
Product Gene Name
Product Synonym Names
Homo sapiens F-box and leucine-rich repeat protein 4 (FBXL4); FBL4; FBL5
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2352C1a
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Molecular Weight
70,097 Da
OMIM
605654
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Applications Tested/Suitable for anti-FBXL4 antibody
Dot Blot (DB)

Quality Control of anti-FBXL4 antibody

Western blot analysis of immunized recombinant protein, using anti-FBXL4 monoclonal antibody.
Mouse Anti-FBXL4 Monoclonal Antibody – Cat# MBS120280

Quality Control #2 of anti-FBXL4 antibody

Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Mouse Anti-FBXL4 Monoclonal Antibody, Quality Control #2 – Cat# MBS120280

Other Notes

Small volumes of anti-FBXL4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FBXL4 purchase

MBS120280 is an antibody targeting FBXL4. Also known as Mouse monoclonal antibody Anti-Human FBXL4. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FBXL4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens F-box and leucine-rich repeat protein 4 (FBXL4), transcript variant 1, mRNA
NCBI Official Synonym Full Names
F-box and leucine-rich repeat protein 4
NCBI Official Symbol
FBXL4
NCBI Official Synonym Symbols
FBL4; FBL5; MTDPS13
UniProt Protein Name
F-box/LRR-repeat protein 4
UniProt Synonym Protein Names
F-box and leucine-rich repeat protein 4; F-box protein FBL4/FBL5
UniProt Gene Name
FBXL4
UniProt Entry Name
FBXL4_HUMAN
NCBI Protein Information
F-box/LRR-repeat protein 4

NCBI Summary for FBXL4

This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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UniProt Comments for FBXL4

FBXL4: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

Chromosomal Location of Human Ortholog: 6q16.1-q16.3

Cellular Component: nucleoplasm; mitochondrial intermembrane space; ubiquitin ligase complex

Biological Process: ubiquitin-dependent protein catabolic process

Disease: Mitochondrial Dna Depletion Syndrome 13 (encephalomyopathic Type)
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FBXL4 antibody

Organs/Tissues associated with anti-FBXL4 antibody

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