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POLS Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS120381

The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. [NCBI Entrez Gene Summary] More details

$575 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
POLS, Monoclonal Antibody
Full Product Name
Mouse monoclonal antibody Anti-Human POLS
Product Gene Name
Product Synonym Names
Homo sapiens polymerase (DNA directed) sigma (POLS), mRNA.; POLK; TRF4; LAK-1; TRF4-1
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2794C4a
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Molecular Weight
59,874 Da
OMIM
605198
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Applications Tested/Suitable for anti-POLS antibody
Dot Blot (DB)

Quality Control of anti-POLS antibody

Western blot analysis of immunized recombinant protein, using anti-POLS monoclonal antibody.
Mouse Anti-POLS Monoclonal Antibody – Cat# MBS120381

Quality Control #2 of anti-POLS antibody

Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Mouse Anti-POLS Monoclonal Antibody, Quality Control #2 – Cat# MBS120381

Other Notes

Small volumes of anti-POLS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for POLS purchase

MBS120381 is an antibody targeting POLS. Also known as Mouse monoclonal antibody Anti-Human POLS. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for POLS. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens PAP associated domain containing 7 (PAPD7), transcript variant 1, mRNA
NCBI Official Synonym Full Names
PAP associated domain containing 7
NCBI Official Symbol
PAPD7
NCBI Official Synonym Symbols
LAK1; POLK; POLS; TRF4; LAK-1; TRF41; TRF4-1; TUTASE5
UniProt Protein Name
Non-canonical poly(A) RNA polymerase PAPD7
UniProt Synonym Protein Names
DNA polymerase sigma; LAK-1; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal uridylyltransferase 5; TUTase 5; Topoisomerase-related function protein 4-1; TRF4-1
UniProt Gene Name
PAPD7
UniProt Entry Name
PAPD7_HUMAN
NCBI Protein Information
non-canonical poly(A) RNA polymerase PAPD7; non-canonical poly(A) RNA polymerase PAPD7; DNA polymerase kappa; DNA polymerase sigma; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; TUTase 5; polymerase (DNA directed) sigma; polymerase (DNA-directed) sigma; terminal uridylyltransferase 5; topoisomerase-related function protein 4-1

NCBI Summary for POLS

The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jan 2010]

UniProt Comments for POLS

POLS: DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion. Does not play a role in replication-dependent histone mRNA degradation. Belongs to the DNA polymerase type-B-like family.

Protein type: EC 2.7.7.19; DNA replication; Transferase; DNA repair, damage

Chromosomal Location of Human Ortholog: 5p15

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: polynucleotide adenylyltransferase activity; DNA binding; SMC protein binding; metal ion binding; DNA-directed DNA polymerase activity

Biological Process: response to drug; mitotic chromosome condensation; cell division; double-strand break repair; sister chromatid cohesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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