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ID1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS120402

The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and… More details

$575 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ID1, Monoclonal Antibody
Full Product Name
Mouse monoclonal antibody Anti-Human ID1
Product Gene Name
anti-ID1 antibody
Product Synonym Names
Homo sapiens inhibitor of DNA binding 1, dominant negative helixloop-helix protein (ID1), transcript variant 1, mRNA.; ID
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2456C1a
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Molecular Weight
15,586 Da
OMIM
600349
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Applications Tested/Suitable for anti-ID1 antibody
Dot Blot (DB), Immunocytochemistry (ICC)

Quality Control of anti-ID1 antibody

Western blot analysis of immunized recombinant protein, using anti-ID1 monoclonal antibody.
Mouse Anti-ID1 Monoclonal Antibody – Cat# MBS120402

Quality Control #2 of anti-ID1 antibody

Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
Mouse Anti-ID1 Monoclonal Antibody, Quality Control #2 – Cat# MBS120402

Immunocytochemistry (ICC) of anti-ID1 antibody

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-ID1 mAb. [Lot No. 2456C1a-1]
Mouse Anti-ID1 Monoclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS120402

Other Notes

Small volumes of anti-ID1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ID1 purchase

MBS120402 is an antibody targeting ID1. Also known as Mouse monoclonal antibody Anti-Human ID1. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ID1. It may not necessarily be applicable to this product.

NCBI GI #
341865544
NCBI GeneID
3397
NCBI Accession #
NP_002156.2
UniProt Secondary Accession #
O00651; O00652; Q16371; Q16377; Q5TE66; Q5TE67; Q969Z7; Q9H0Z5; Q9H109; A8K537; E1P5L4
UniProt Related Accession #
P41134
GenBank Nucleotide #
NM_002165
NCBI Official Full Name
Homo sapiens inhibitor of DNA binding 1, dominant negative helix-loop-helix protein (ID1), transcript variant 1, mRNA
NCBI Official Synonym Full Names
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
NCBI Official Symbol
ID1
NCBI Official Synonym Symbols
ID; bHLHb24
UniProt Protein Name
DNA-binding protein inhibitor ID-1
UniProt Synonym Protein Names
Class B basic helix-loop-helix protein 24; bHLHb24; Inhibitor of DNA binding 1; Inhibitor of differentiation 1
Protein Family
DNA-binding protein inhibitor
UniProt Gene Name
ID1
UniProt Entry Name
ID1_HUMAN
NCBI Protein Information
DNA-binding protein inhibitor ID-1; class B basic helix-loop-helix protein 24; dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein); inhibitor of differentiation 1

UniProt Comments for ID1

ID1: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 20q11

Cellular Component: nucleoplasm; Golgi apparatus; nucleus

Molecular Function: protein dimerization activity; protein binding; transcription factor activity

Biological Process: circadian rhythm; transcription, DNA-dependent; collagen metabolic process; protein destabilization; blood vessel endothelial cell migration; negative regulation of transcription factor activity; heart development; negative regulation of transcription from RNA polymerase II promoter; regulation of angiogenesis; negative regulation of DNA binding; BMP signaling pathway; response to antibiotic; regulation of MAPKKK cascade; transforming growth factor beta receptor signaling pathway; blood vessel morphogenesis; negative regulation of osteoblast differentiation; angiogenesis; endothelial cell morphogenesis; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis
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Research Articles on ID1

1. High Id1b, generated by alternative splicing, maintains cell quiescence and confers self-renewal and cancer stem cell-like properties.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ID1 antibody

 Products by Pathway  Pathway Diagram
 ALK1 Signaling Events Pathway antibodies  ALK1 Signaling Events Pathway Diagram
 Cellular Senescence Pathway antibodies  Cellular Senescence Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 IL-3 Signaling Pathway antibodies  IL-3 Signaling Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
 Notch-mediated HES/HEY Network Pathway antibodies  Notch-mediated HES/HEY Network Pathway Diagram
 Oncogene Induced Senescence Pathway antibodies  Oncogene Induced Senescence Pathway Diagram

Diseases associated with anti-ID1 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >132 publications with ID1 and Carcinoma
 Breast Neoplasms Antibodies  >57 publications with ID1 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >53 publications with ID1 and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >51 publications with ID1 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >39 publications with ID1 and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >36 publications with ID1 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >36 publications with ID1 and Lung Neoplasms
 Brain Diseases Antibodies  >25 publications with ID1 and Brain Diseases
 Hypertension Antibodies  >24 publications with ID1 and Hypertension
 Cardiovascular Diseases Antibodies  >24 publications with ID1 and Cardiovascular Diseases

Organs/Tissues associated with anti-ID1 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >255 publications with ID1 and Bone
 Blood Antibodies  >163 publications with ID1 and Blood
 Vascular Antibodies  >118 publications with ID1 and Vascular
 Muscle Antibodies  >102 publications with ID1 and Muscle
 Lung Antibodies  >80 publications with ID1 and Lung
 Brain Antibodies  >79 publications with ID1 and Brain
 Liver Antibodies  >69 publications with ID1 and Liver
 Prostate Antibodies  >64 publications with ID1 and Prostate
 Embryonic Tissue Antibodies  >60 publications with ID1 and Embryonic Tissue
 Heart Antibodies  >37 publications with ID1 and Heart
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