Saccharomyces Cerevisiae ERI1 Recombinant Protein – Cat# MBS1204754

Phosphatidylinositol N-Acetylglucosaminyltransferase ERI1 Subunit (ERI1) Saccharomyces Cerevisiae Recombinant Protein

Name: ERI1 Recombinant Protein; Saccharomyces Cerevisiae; MyBioSource
Brand: MyBioSource
SKU: MBS1204754
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1204754

MBS1204754 is a recombinant protein targeting ERI1. Also known as Recombinant Saccharomyces cerevisiae Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit (ERI1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit (ERI1), Recombinant Protein

Full Product Name

Recombinant Saccharomyces cerevisiae Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit (ERI1)

Product Gene Name

ERI1 recombinant protein

Product Synonym Gene Name

ERI1; RIN1

Product Synonym Names

Recombinant Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit (ERI1); Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit; Endoplasmic reticulum-associated Ras inhibitor protein 1

Sequence

MRPRDQGFLV LGFTYSVLLI SLATFYWLRN NDSFLHYWCV LLLCPATLWL WALIAWCDSE MFASSKDE

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

8,039 Da

Sequence Positions

1-68

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: XVI; NC_001148.4 (366529..366735, complement). Location: chromosome: XVI

3D Structure

ModBase 3D Structure for P62651

Species

Saccharomyces cerevisiae (strain 204508 / S288c) (Baker's yeast)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ERI1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ERI1. It may not necessarily be applicable to this product.

NCBI GI #

23270400

NCBI GeneID

856008

NCBI Accession #

NP_690846.1

UniProt Primary Accession #

P62651

UniProt Secondary Accession #

D6W3S0

UniProt Related Accession #

P62651

GenBank Nucleotide #

NM_001184515.1

NCBI Official Full Name

Eri1p

NCBI Official Symbol

ERI1

NCBI Official Synonym Symbols

RIN1

UniProt Protein Name

Phosphatidylinositol N-acetylglucosaminyltransferase ERI1 subunit

UniProt Synonym Protein Names

Endoplasmic reticulum-associated Ras inhibitor protein 1

Protein Family

3'-5' exonuclease

UniProt Gene Name

ERI1

UniProt Synonym Gene Names

RIN1

UniProt Entry Name

ERI1_YEAST

NCBI Protein Information

Eri1p

UniProt Comments for ERI1

Function: Probable component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI-anchors for cell surface proteins. Ras may inhibit the enzyme activity of the GPI-GnT complex via the association between ERI1 and RAS2. Ref.3 Ref.4

Pathway: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.

Subunit structure: Interacts with GTP-bound RAS2 in an effector loop-dependent manner. Interacts with GPI2, suggesting that it is a component of the GPI-GnT complex, probably composed of GPI1, GPI2, GPI3, GPI15 and ERI1. Ref.3 Ref.4

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein Ref.3.

Disruption phenotype: Defects cause hyperactive Ras phenotypes, probably due to diminished GPI-anchor protein production. Ref.3

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ERI1 recombinant protein

Reference Product	PubMed Publications
YIL156W-B recombinant protein	>1 publications with ERI1 and YIL156W-B
YJL127C-B recombinant protein	>1 publications with ERI1 and YJL127C-B

Pathways associated with ERI1 recombinant protein

Products by Pathway	Pathway Diagram
Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies	Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram
Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway antibodies	Glycosylphosphatidylinositol(GPI)-anchor Biosynthesis Pathway Diagram