Human SLC24A1 Recombinant Protein – Cat# MBS1208685

Sodium/Potassium/Calcium Exchanger 1 (SLC24A1) Human Recombinant Protein

Name: SLC24A1 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1208685
Price: 1895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1208685

MBS1208685 is a recombinant protein targeting SLC24A1. Also known as Recombinant Human Sodium/potassium/calcium exchanger 1 (SLC24A1) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1895 / 1 mg (E-Coli) +2 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Sodium/potassium/calcium exchanger 1 (SLC24A1), Recombinant Protein

Full Product Name

Recombinant Human Sodium/potassium/calcium exchanger 1 (SLC24A1) , partial

Product Gene Name

SLC24A1 recombinant protein

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

117,632 Da

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

603617

3D Structure

ModBase 3D Structure for O60721

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SLC24A1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC24A1. It may not necessarily be applicable to this product.

NCBI GI #

666335647

NCBI GeneID

9187

NCBI Accession #

NP_001287960.1

UniProt Primary Accession #

O60721

UniProt Secondary Accession #

O43485; O75184; Q17RM9

UniProt Related Accession #

O60721

GenBank Nucleotide #

NM_001301031.1

NCBI Official Full Name

sodium/potassium/calcium exchanger 1 isoform 3

NCBI Official Synonym Full Names

solute carrier family 24 member 1

NCBI Official Symbol

SLC24A1

NCBI Official Synonym Symbols

NCKX; RODX; NCKX1; CSNB1D; HsT17412

UniProt Protein Name

Sodium/potassium/calcium exchanger 1

UniProt Synonym Protein Names

Na(+)/K(+)/Ca(2+)-exchange protein 1; Retinal rod Na-Ca+K exchanger; Solute carrier family 24 member 1

Protein Family

Sodium/potassium/calcium exchanger

UniProt Gene Name

SLC24A1

UniProt Synonym Gene Names

KIAA0702; NCKX1

NCBI Protein Information

sodium/potassium/calcium exchanger 1

NCBI Summary for SLC24A1

This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. The encoded protein plays an important role in sodium/calcium exchange in retinal rod and cone photoreceptors by mediating the extrusion of one calcium ion and one potassium ion in exchange for four sodium ions. Mutations in this gene may play a role in congenital stationary night blindness. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

UniProt Comments for SLC24A1

Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca2+ and 1 K+ in exchange for 4 Na+.

Research Articles on SLC24A1

1. The index patient and his affected brother carry a homozygous single-nucleotide variants (SNVs) in sodium-calcium, potassium exchanger (SLC24A1) (c.2401G > T).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SLC24A1 recombinant protein

Products by Pathway	Pathway Diagram
Activation Of The Phototransduction Cascade Pathway antibodies	Activation Of The Phototransduction Cascade Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Associated With Visual Transduction Pathway antibodies	Diseases Associated With Visual Transduction Pathway Diagram
Phototransduction Pathway antibodies	Phototransduction Pathway Diagram
Phototransduction Pathway antibodies	Phototransduction Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Sodium/Calcium Exchangers Pathway antibodies	Sodium/Calcium Exchangers Pathway Diagram
The Phototransduction Cascade Pathway antibodies	The Phototransduction Cascade Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram

Organs/Tissues associated with SLC24A1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>3 publications with SLC24A1 and Eye
Brain Antibodies	>1 publications with SLC24A1 and Brain
Lung Antibodies	>1 publications with SLC24A1 and Lung