• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Delta (14)-Sterol Reductase (TM7SF2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1212904

MBS1212904 is a recombinant protein targeting TM7SF2. Also known as Recombinant Human Delta (14)-sterol reductase (TM7SF2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Delta (14)-sterol reductase (TM7SF2), Recombinant Protein
Full Product Name
Recombinant Human Delta (14)-sterol reductase (TM7SF2)
Product Synonym Gene Name
TM7SF2; ANG1
Product Synonym Names
Recombinant Delta (14)-sterol reductase (TM7SF2); Delta(14)-sterol reductase; Delta-14-SR EC= 1.3.1.70; Another new gene 1 protein C-14 sterol reductase Putative sterol reductase SR-1 Sterol C14-reductase Transmembrane 7 superfamily member 2
Sequence
MAPTQGPRAP LEFGGPLGAA ALLLLLPATM FHLLLAARSG PARLLGPPAS LPGLEVLWSP RALLLWLAWL GLQAALYLLP ARKVAEGQEL KDKSRLRYPI NGFQALVLTA LLVGLGMSAG LPLGALPEML LPLAFVATLT AFIFSLFLYM KAQVAPVSAL APGGNSGNPI YDFFLGRELN PRICFFDFKY FCELRPGLIG WVLINLALLM KEAELRGSPS LAMWLVNGFQ LLYVGDALWH EEAVLTTMDI THDGFGFMLA FGDMAWVPFT YSLQAQFLLH HPQPLGLPMA SVICLINATG YYIFRGANSQ KNTFRKNPSD PRVAGLETIS TATGRKLLVS GWWGMVRHPN YLGDLIMALA WSLPCGVSHL LPYFYLLYFT ALLVHREARD ERQCLQKYGL AWQEYCRRVP YRIMPYIY
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
46,406 Da
Sequence Positions
1-418
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Chromosome Location
Chromosome: 11; NC_000011.9 (64879341..64883707). Location: 11q13
OMIM
603414
3D Structure
ModBase 3D Structure for O76062
Species
Homo sapiens (Human)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TM7SF2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TM7SF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
delta(14)-sterol reductase
NCBI Official Synonym Full Names
transmembrane 7 superfamily member 2
NCBI Official Symbol
TM7SF2
NCBI Official Synonym Symbols
ANG1; NET47; DHCR14A
UniProt Protein Name
Delta(14)-sterol reductase
UniProt Synonym Protein Names
Another new gene 1 protein; C-14 sterol reductase; Putative sterol reductase SR-1; Sterol C14-reductase; Transmembrane 7 superfamily member 2
UniProt Gene Name
TM7SF2
UniProt Synonym Gene Names
ANG1; Delta-14-SR
UniProt Entry Name
ERG24_HUMAN
NCBI Protein Information
delta(14)-sterol reductase; delta(14)-sterol reductase; delta-14-SR; sterol C14-reductase; C-14 sterol reductase; another new gene 1 protein; putative sterol reductase SR-1

UniProt Comments for TM7SF2

TM7SF2: Involved in the conversion of lanosterol to cholesterol. Belongs to the ERG4/ERG24 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.3.1.70; Membrane protein, multi-pass; Oxidoreductase; Membrane protein, integral; Endoplasmic reticulum; Lipid Metabolism - steroid biosynthesis

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to plasma membrane; receptor complex

Molecular Function: delta14-sterol reductase activity

Biological Process: cholesterol biosynthetic process
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000