Xenopus Laevis creb3l2 Recombinant Protein – Cat# MBS1215671

Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 2 (creb3l2) Xenopus Laevis Recombinant Protein

Name: creb3l2 Recombinant Protein; Xenopus Laevis; MyBioSource
Brand: MyBioSource
SKU: MBS1215671
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1215671

MBS1215671 is a recombinant protein targeting creb3l2. Also known as Recombinant Xenopus laevis Cyclic AMP-responsive element-binding protein 3-like protein 2 (creb3l2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cyclic AMP-responsive element-binding protein 3-like protein 2 (creb3l2), Recombinant Protein

Full Product Name

Recombinant Xenopus laevis Cyclic AMP-responsive element-binding protein 3-like protein 2 (creb3l2)

Product Gene Name

creb3l2 recombinant protein

Product Synonym Names

Cyclic AMP-responsive element-binding protein 3-like protein 2; cAMP-responsive element-binding protein 3-like protein 2Cleaved into the following chain:; 1. Processed cyclic AMP-responsive element-binding protein 3-like protein 2

Sequence

MEIMESGDPV IQWDRKLSEL SEAAESDSLY NNTPFSELLD DSALLDVLGQ LMGDPFLTEK YEMMEVEMNP SSPSPMIKAE HSYSLCGDSR PQSPFTHASS DDNFSDTDLT GDDWCLNGEL TATTPTTKIK VEIPLEETPG LTPSVTLATS AVSASPEVGV SSQLPVPEQV KLLSPVALPQ IKLEPHEVDQ FLNLCPKEVA PTEALQMPPT PPSSHGSDSE GGQSPTRSLP PSSPVQSQAG GKMAARSPSA LSNSPLLTAP HKLQGSGPLM LTEEEKRTLV AEGYPIPTKL PLTKAEEKAL KKIRRKIKNK ISAQESRRKK KEYMDSLEKR VENSSSENSE LRKKVEVLES TNRTLLQQLQ RLQAMVTGKV TRSCKAAGTQ TG

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

57,625 Da

Sequence Positions

1-382

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for A2VD01

Species

Xenopus laevis (African clawed frog)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of creb3l2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for creb3l2. It may not necessarily be applicable to this product.

NCBI GI #

148231257

NCBI GeneID

100037168

NCBI Accession #

NP_001091333.1

UniProt Primary Accession #

A2VD01

UniProt Related Accession #

A2VD01

GenBank Nucleotide #

NM_001097864.1

NCBI Official Full Name

cyclic AMP-responsive element-binding protein 3-like protein 2

NCBI Official Synonym Full Names

cAMP responsive element binding protein 3-like 2<

NCBI Official Symbol

creb3l2

NCBI Official Synonym Symbols

bbf2h7

UniProt Protein Name

Cyclic AMP-responsive element-binding protein 3-like protein 2

Protein Family

Cyclic AMP-responsive element-binding protein 3-like protein

UniProt Gene Name

creb3l2

UniProt Synonym Gene Names

cAMP-responsive element-binding protein 3-like protein 2

UniProt Entry Name

CR3L2_XENLA

NCBI Protein Information

cyclic AMP-responsive element-binding protein 3-like protein 2; cAMP-responsive element-binding protein 3-like protein 2

UniProt Comments for creb3l2

Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/mbtps1 and S2P/mbtps2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis. May protect neuroblastoma cells from ER stress-induced death. In vitro activates transcription of target genes via direct binding to the CRE site.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with creb3l2 recombinant protein

Products by Pathway	Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Adrenergic Signaling In Cardiomyocytes Pathway antibodies	Adrenergic Signaling In Cardiomyocytes Pathway Diagram
Melanogenesis Pathway antibodies	Melanogenesis Pathway Diagram
Melanogenesis Pathway antibodies	Melanogenesis Pathway Diagram

Diseases associated with creb3l2 recombinant protein

Disease Name	Pubmed Publications
Fibrosis Antibodies	>2 publications with creb3l2 and Fibrosis
Neoplasm Metastasis Antibodies	>2 publications with creb3l2 and Neoplasm Metastasis
Heart Diseases Antibodies	>1 publications with creb3l2 and Heart Diseases