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TUBGCP4 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS001220

MBS001220 is an antibody targeting TUBGCP4. Also known as Rabbit TUBGCP4 Antibody. Reactive in Human, mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TUBGCP4, Antibody
Full Product Name
Rabbit TUBGCP4 Antibody
Product Gene Name
Host
Rabbit
Species Reactivity
Human, mouse
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Molecular Weight
76,089 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (43663313..43698258). Location: 15q15
OMIM
609610
3D Structure
ModBase 3D Structure for Q9UGJ1
Applications Tested/Suitable for anti-TUBGCP4 antibody
ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-TUBGCP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TUBGCP4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gamma-tubulin complex component 4
NCBI Official Synonym Full Names
tubulin, gamma complex associated protein 4
NCBI Official Symbol
TUBGCP4
NCBI Official Synonym Symbols
76P; GCP4; h76p; GCP-4; hGCP4; hGrip76
UniProt Protein Name
Gamma-tubulin complex component 4
UniProt Synonym Protein Names
Gamma-ring complex protein 76 kDa
UniProt Gene Name
TUBGCP4
UniProt Synonym Gene Names
76P; GCP4; GCP-4; hGCP4; h76p; hGrip76
UniProt Entry Name
GCP4_HUMAN
NCBI Protein Information
gamma-tubulin complex component 4; gamma-ring complex protein 76 kDa; gamma tubulin ring complex protein (76p gene)

NCBI Summary for TUBGCP4

This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
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UniProt Comments for TUBGCP4

TUBGCP4: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Belongs to the TUBGCP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q15

Cellular Component: microtubule cytoskeleton; spindle pole; microtubule; centrosome; gamma-tubulin ring complex; recycling endosome; membrane; cytosol

Molecular Function: structural constituent of cytoskeleton

Biological Process: protein complex assembly; mitotic cell cycle; G2/M transition of mitotic cell cycle; microtubule nucleation

Disease: Microcephaly And Chorioretinopathy, Autosomal Recessive, 3
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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