Human CDC40 Recombinant Protein – Cat# MBS1220145

Pre-Mrna-Processing Factor 17 (CDC40) Human Recombinant Protein

Name: CDC40 Recombinant Protein; Pre-Mrna-Processing Factor 17; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1220145
Price: 1370 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1220145

Pre-mRNA splicing occurs in two sequential transesterification steps. This protein is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in… More details

$1370 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pre-mRNA-processing factor 17 (CDC40), Recombinant Protein

Full Product Name

Recombinant Human Pre-mRNA-processing factor 17 (CDC40)

Product Gene Name

CDC40 recombinant protein

Sequence

MSAAIAALAA SYGSGSGSES DSDSESSRCP LPAADSLMHL TKSPSSKPSL AVAVDSAPEV AVKEDLETGV HLDPAVKEVQ YNPTYETMFA PEFGPENPFR TQQMAAPRNM LSGYAEPAHI NDFMFEQQRR TFATYGYALD PSLDNHQVSA KYIGSVEEAE KNQGLTVFET GQKKTEKRKK FKENDASNID GFLGPWAKYV DEKDVAKPSE EEQKELDEIT AKRQKKGKQE EEKPGEEKTI LHVKEMYDYQ GRSYLHIPQD VGVNLRSTMP PEKCYLPKKQ IHVWSGHTKG VSAVRLFPLS GHLLLSCSMD CKIKLWEVYG ERRCLRTFIG HSKAVRDICF NTAGTQFLSA AYDRYLKLWD TETGQCISRF TNRKVPYCVK FNPDEDKQNL FVAGMSDKKI VQWDIRSGEI VQEYDRHLGA VNTIVFVDEN RRFVSTSDDK SLRVWEWDIP VDFKYIAEPS MHSMPAVTLS PNGKWLACQS MDNQILIFGA QNRFRLNKKK IFKGHMVAGY ACQVDFSPDM SYVISGDGNG KLNIWDWKTT KLYSRFKAHD KVCIGAVWHP HETSKVITCG WDGLIKLWD

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

65,521 Da

Sequence Positions

1-579, Full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

605585

3D Structure

ModBase 3D Structure for O60508

Species

Human

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CDC40 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDC40 purchase

MBS1220145 is a recombinant protein targeting CDC40. Also known as Recombinant Human Pre-mRNA-processing factor 17 (CDC40). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for CDC40. It may not necessarily be applicable to this product.

NCBI GI #

7706657

NCBI GeneID

51362

NCBI Accession #

NP_056975.1

UniProt Primary Accession #

O60508

UniProt Secondary Accession #

O75471; Q5SRN0; Q9UPG1; B2RBC5

UniProt Related Accession #

O60508

GenBank Nucleotide #

NM_015891.2

NCBI Official Full Name

pre-mRNA-processing factor 17

NCBI Official Synonym Full Names

cell division cycle 40

NCBI Official Symbol

CDC40

NCBI Official Synonym Symbols

EHB3; PRP17; PRPF17

UniProt Protein Name

Pre-mRNA-processing factor 17

UniProt Synonym Protein Names

Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; PRP17 homolog; hPRP17

UniProt Gene Name

CDC40

UniProt Synonym Gene Names

EHB3; PRP17; PRPF17; Ehb3; hPRP17

NCBI Protein Information

pre-mRNA-processing factor 17

NCBI Summary for CDC40

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]

UniProt Comments for CDC40

Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.

Research Articles on CDC40

1. HBx activates NF-kappaB to promote the expression of miR1269b, which augments CDC40 expression, contributing to malignancy in hepatocellular cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CDC40 recombinant protein

Reference Product	PubMed Publications
DHX38 recombinant protein	>1 publications with CDC40 and DHX38

Pathways associated with CDC40 recombinant protein

Products by Pathway	Pathway Diagram
Cleavage Of Growing Transcript In The Termination Region Pathway antibodies	Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies	Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
RNA Polymerase II Transcription Pathway antibodies	RNA Polymerase II Transcription Pathway Diagram
RNA Polymerase II Transcription Termination Pathway antibodies	RNA Polymerase II Transcription Termination Pathway Diagram
Spliceosome Pathway antibodies	Spliceosome Pathway Diagram
Spliceosome Pathway antibodies	Spliceosome Pathway Diagram
Spliceosome, 35S U5-snRNP Pathway antibodies	Spliceosome, 35S U5-snRNP Pathway Diagram
Transport Of Mature Transcript To Cytoplasm Pathway antibodies	Transport Of Mature Transcript To Cytoplasm Pathway Diagram
Transport Of Mature MRNA Derived From An Intron-Containing Transcript Pathway antibodies	Transport Of Mature MRNA Derived From An Intron-Containing Transcript Pathway Diagram

Diseases associated with CDC40 recombinant protein

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>1 publications with CDC40 and Kidney Diseases

Organs/Tissues associated with CDC40 recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with CDC40 and Muscle
Ovary Antibodies	>1 publications with CDC40 and Ovary
Prostate Antibodies	>1 publications with CDC40 and Prostate
Uterus Antibodies	>1 publications with CDC40 and Uterus
Heart Antibodies	>1 publications with CDC40 and Heart
Kidney Antibodies	>1 publications with CDC40 and Kidney
Testis Antibodies	>1 publications with CDC40 and Testis
Brain Antibodies	>1 publications with CDC40 and Brain