Human TAF5L Recombinant Protein – Cat# MBS1220417

TAF5-Like RNA Polymerase II P300/CBP-Associated Factor-Associated Factor 65 Kda Subunit 5l (TAF5L) Human Recombinant Protein

Name: TAF5L Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1220417
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1220417

MBS1220417 is a recombinant protein targeting TAF5L. Also known as Recombinant Human TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. TAF5L; PAF65B More details

$455 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L), Recombinant Protein

Full Product Name

Recombinant Human TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L)

Product Gene Name

TAF5L recombinant protein

Product Synonym Gene Name

TAF5L; PAF65B

Product Synonym Names

TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; PCAF-associated factor 65 beta; PAF65-beta

Sequence

MKRVRTEQIQ MAVSCYLKRR QYVDSDGPLK QGLRLSQTAE EMAANLTVQS ESGCANIVSA APCQAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNLVQN SPKSTVESFY SRFHGMFLQN ASQKDVIEQL QTTQTIQDIL SNFKLRAFLD NKYVVRLQED SYNYLIRYLQ SDNNTALCKV LTLHIHLDVQ PAKRTDYQLY ASGSSSRSEN NGLEPPDMPS PILQNEAALE VLQESIKRVK DGPPSLTTIC FYAFYNTEQL LNTAEISPDS KLLAAGFDNS CIKLWSLRSK KLKSEPHQVD VSRIHLACDI LEEEV

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

64 kDa

Sequence Positions

1-325aa; Full Length of Isoform 2

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O75529

Species

Homo sapiens (Human)

Product Categories/Family for TAF5L recombinant protein

Epigenetics and Nuclear Signaling

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TAF5L recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TAF5L. It may not necessarily be applicable to this product.

NCBI GI #

69122931

NCBI GeneID

27097

NCBI Accession #

NP_001020418.1

UniProt Primary Accession #

O75529

UniProt Secondary Accession #

Q5TDI5; Q5TDI6; Q8IW31

UniProt Related Accession #

O75529

GenBank Nucleotide #

NM_001025247.1

NCBI Official Full Name

TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L isoform b

NCBI Official Synonym Full Names

TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

NCBI Official Symbol

TAF5L

NCBI Official Synonym Symbols

PAF65B

UniProt Protein Name

TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

UniProt Synonym Protein Names

PCAF-associated factor 65 beta; PAF65-beta

Protein Family

TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor

UniProt Gene Name

TAF5L

UniProt Synonym Gene Names

PAF65B; PAF65-beta

UniProt Entry Name

TAF5L_HUMAN

NCBI Protein Information

TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; PAF65-beta; PCAF associated factor 65 beta; PCAF-associated factor 65 beta

NCBI Summary for TAF5L

The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for TAF5L

TAF5L: Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Belongs to the WD repeat TAF5 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 1q42.13

Cellular Component: nucleoplasm; nucleus

Molecular Function: histone acetyltransferase activity; transcription coactivator activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; regulation of transcription, DNA-dependent

Research Articles on TAF5L

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TAF5L recombinant protein

Products by Pathway	Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Chromatin Modifying Enzymes Pathway antibodies	Chromatin Modifying Enzymes Pathway Diagram
Chromatin Organization Pathway antibodies	Chromatin Organization Pathway Diagram
HATs Acetylate Histones Pathway antibodies	HATs Acetylate Histones Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram

Diseases associated with TAF5L recombinant protein

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>1 publications with TAF5L and Lung Diseases
Neoplasm Metastasis Antibodies	>1 publications with TAF5L and Neoplasm Metastasis
Breast Neoplasms Antibodies	>1 publications with TAF5L and Breast Neoplasms
Adenocarcinoma Antibodies	>1 publications with TAF5L and Adenocarcinoma
Lung Neoplasms Antibodies	>1 publications with TAF5L and Lung Neoplasms
Inflammation Antibodies	>1 publications with TAF5L and Inflammation

Organs/Tissues associated with TAF5L recombinant protein

Organ/Tissue Name	Pubmed Publications
Ovary Antibodies	>1 publications with TAF5L and Ovary
Lung Antibodies	>1 publications with TAF5L and Lung
Lymph Node Antibodies	>1 publications with TAF5L and Lymph Node
Pancreas Antibodies	>1 publications with TAF5L and Pancreas
Testis Antibodies	>1 publications with TAF5L and Testis
Embryonic Tissue Antibodies	>1 publications with TAF5L and Embryonic Tissue