COVID 19 Nucleocapsid (Np) Coronavirus (COVID-19) Antibody – Rabbit Monoclonal

Capture Antibody: COVID-19 Clone #COV-NP-5B1 (MBS122273)
Detection Antibody: COVID-19 Clone #COV-NP-11A7 (MBS122275)
Comments: The following pairs have high sensitivity and specificity in lateral flow applications; the pairs have been tested with real SARS-CoV-2 virus and also used in clinical research trials: Capture: COV-NP-Rb-3; Detection: COV-NP-Rb-1 or COV-NP-Rb-2 or COV-NP-Rb-4. Capture: COV-NP-Rb-1; Detector: COV-NP-Rb-2 or COV-NP-Rb-3. The four rabbit monoclonal antibody clones COV-NP-5B1 (Cat no COV-NP-Rb-1), COV-NP-5E2 (Cat no. COV-NP-Rb-2), COV-NP-11A7 (COV-NP-Rb-3), COV-NP-11H9 (COV-NP-Rb-4) recognize different epitopes. Since the clones recognize different epitopes, using combinations of clones (mixing clones together) can increase sensitivity. Specific epitope information is company proprietary information.

Lateral flow: Laboratory data shows that the analytical sensitivity with recombinant nucleoprotein is about 0.1-0.5ng/ml on gold lateral flow format. Fluorescent bead format can also be used to develop lateral flow assays

Advantages of rabbit monoclonal antibodies compared to using rabbit polyclonal antibodies: Mixing together the four rabbit monoclonal antibodies will likely have less lot to lot variation, larger lot sizes and higher sensitivity than rabbit polyclonal antibodies.

Capture Antibody: COVID-19 Clone #COV-NP-11A7 (MBS122275)
Detection Antibody: COVID-19 Clone #COV-NP-5B1 (MBS122273)
Comments: The following pairs have high sensitivity and specificity in lateral flow applications; the pairs have been tested with real SARS-CoV-2 virus and also used in clinical research trials: Capture: COV-NP-Rb-3; Detection: COV-NP-Rb-1 or COV-NP-Rb-2 or COV-NP-Rb-4. Capture: COV-NP-Rb-1; Detector: COV-NP-Rb-2 or COV-NP-Rb-3. The four rabbit monoclonal antibody clones COV-NP-5B1 (Cat no COV-NP-Rb-1), COV-NP-5E2 (Cat no. COV-NP-Rb-2), COV-NP-11A7 (COV-NP-Rb-3), COV-NP-11H9 (COV-NP-Rb-4) recognize different epitopes. Since the clones recognize different epitopes, using combinations of clones (mixing clones together) can increase sensitivity. Specific epitope information is company proprietary information.

Lateral flow: Laboratory data shows that the analytical sensitivity with recombinant nucleoprotein is about 0.1-0.5ng/ml on gold lateral flow format. Fluorescent bead format can also be used to develop lateral flow assays

Advantages of rabbit monoclonal antibodies compared to using rabbit polyclonal antibodies: Mixing together the four rabbit monoclonal antibodies will likely have less lot to lot variation, larger lot sizes and higher sensitivity than rabbit polyclonal antibodies.