Rat MIP Recombinant Protein – Cat# MBS1226992

Lens Fiber Major Intrinsic Protein (MIP) Rat Recombinant Protein

Name: MIP Recombinant Protein; Lens Fiber Major Intrinsic Protein; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS1226992
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1226992

MBS1226992 is a recombinant protein targeting Mip. Also known as Recombinant Rat Lens fiber major intrinsic protein (Mip). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lens fiber major intrinsic protein (Mip), Recombinant Protein

Full Product Name

Recombinant Rat Lens fiber major intrinsic protein (Mip)

Product Gene Name

Mip recombinant protein

Product Synonym Gene Name

Mip

Product Synonym Names

Recombinant Lens fiber major intrinsic protein (Mip); Lens fiber major intrinsic protein; Aquaporin-0 MIP26; MP26

Sequence

ELRSASFWRA IFAEFFATLF YVFFGLGSSL RWAPGPLHVL QVALAFGLAL ATLVQTVGHI SGAHVNPAVT FAFLVGSQMS LLRAFCYIAA QLLGAVAGAA VLYSVTPPAV RGNLALNTLH AGVSVGQATT VEIFLTLQFV LCIFATYDER RNGRMGSVAL AVGFSLTLGH LFGMYYTGAG MNPARSFAPA ILTRNFSNHW VYWVGPIIGG GLGSLLYDFL LFPRLKSVSE RLSILKGARP SDSNGQPEGT GEPVELKTQA L

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

27,891 Da

Sequence Positions

1-261

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 7; NC_005106.3 (2614619..2621871). Location: 7q11

3D Structure

ModBase 3D Structure for P09011

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Mip recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Mip. It may not necessarily be applicable to this product.

NCBI GI #

127106

NCBI GeneID

25480

NCBI Accession #

P09011.2

UniProt Primary Accession #

P09011

UniProt Related Accession #

P09011

NCBI Official Full Name

Lens fiber major intrinsic protein

NCBI Official Synonym Full Names

major intrinsic protein of lens fiber

NCBI Official Symbol

Mip

NCBI Official Synonym Symbols

Aqp0

UniProt Protein Name

Lens fiber major intrinsic protein

UniProt Synonym Protein Names

Aquaporin-0; MIP26

Protein Family

Allatostatins

UniProt Gene Name

Mip

UniProt Synonym Gene Names

MP26

UniProt Entry Name

MIP_RAT

NCBI Protein Information

lens fiber major intrinsic protein; MP26; MIP26; aquaporin-0; major intrinsic protein of eye lens fiber

NCBI Summary for Mip

human homolog is a member of the aquaporin family of water transporters [RGD, Feb 2006]

UniProt Comments for Mip

AQP0: major intrinsic protein of lens fiber. A member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. May be responsible for regulating the osmolarity of the lens. Defects in MIP are a cause of autosomal recessive congenital cataract.

Protein type: Channel, misc.; Membrane protein, multi-pass; Transporter, aquaporin family; Membrane protein, integral

Cellular Component: intracellular canaliculus; membrane; intracellular membrane-bound organelle; integral to plasma membrane; gap junction; integral to membrane; plasma membrane

Molecular Function: calmodulin binding; water channel activity; structural constituent of eye lens; glycerol channel activity

Biological Process: lens development in camera-type eye; glycerol transport; cellular water homeostasis; visual perception; canalicular bile acid transport; water transport; transmembrane transport

Research Articles on Mip

1. These findings suggest that AQP0 plays an important role in controlling lens ascorbic acid content.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Mip recombinant protein

Reference Product	PubMed Publications
Lim2 recombinant protein	>8 publications with Mip and Lim2
Gja3 recombinant protein	>6 publications with Mip and Gja3
Cryba1 recombinant protein	>6 publications with Mip and Cryba1
Bfsp1 recombinant protein	>2 publications with Mip and Bfsp1
Cryba2 recombinant protein	>2 publications with Mip and Cryba2

Pathways associated with Mip recombinant protein

Products by Pathway	Pathway Diagram
Aquaporin-mediated Transport Pathway antibodies	Aquaporin-mediated Transport Pathway Diagram
Passive Transport By Aquaporins Pathway antibodies	Passive Transport By Aquaporins Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram

Organs/Tissues associated with Mip recombinant protein

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>348 publications with Mip and Eye
Uncharacterized Tissue Antibodies	>5 publications with Mip and Uncharacterized Tissue