Mouse ARG2 Recombinant Protein – Cat# MBS1227644

Arginase-2 (ARG2) Mouse Recombinant Protein

Name: ARG2 Recombinant Protein; Arginase-2; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS1227644
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1227644

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. More details

$455 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Arginase-2 (Arg2), Recombinant Protein

Full Product Name

Recombinant Mouse Arginase-2, mitochondrial

Product Gene Name

Arg2 recombinant protein

Product Synonym Names

Kidney-type arginase; Non-hepatic arginase; Type II arginase

Sequence

VHSVAIVGAP FSRGQKKLGV EYGPAAIREA GLLKRLSRLG CHLKDFGDLS FTNVPQDDPY NNLVVYPRSV GLANQELAEV VSRAVSGGYS CVTMGGDHSL AIGTIIGHAR HRPDLCVIWV DAHADINTPL TTVSGNIHGQ PLSFLIKELQ DKVPQLPGFS WIKPCLSPPN IVYIGLRDVE PPEHFILKNY DIQYFSMREI DRLGIQKVME QTFDRLIGKR QRPIHLSFDI DAFDPKLAPA TGTPVVGGLT YREGVYITEE IHNTGLLSAL DLVEVNPHLA TSEEEAKATA RLAVDVIASS FGQTREGGHI VYDHLPTPSS PHESENEECV RI

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

Molecular Weight

52.4 kDa

Sequence Positions

23-354aa; Full Length of Mature Protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O08691

Production Note

Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Product References and Citations for Arg2 recombinant protein

Cloning and characterization of the mouse and rat type II arginase genes.Iyer R.K., Bando J.M., Jenkinson C.P., Vockley J.G., Kim P.S., Kern R.M., Cederbaum S.D., Grody W.W.Mol. Genet. Metab. 63:168-175(1998) Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells.Morris S.M. Jr., Kepka-Lenhart D., Chen L.C.Am. J. Physiol. 275:E740-E747(1998) Structure of the murine arginase II gene.Shi O.U., Kepka-Lenhart D., Morris S.M. Jr., O'Brien W.E.Mamm. Genome 9:822-824(1998) Lubec G., Sunyer B., Chen W.-Q.Submitted (JAN-2009) to UniProtKB

Other Notes

Small volumes of Arg2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Arg2 purchase

MBS1227644 is a recombinant protein targeting Arg2. Also known as Recombinant Mouse Arginase-2, mitochondrial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Arg2. It may not necessarily be applicable to this product.

NCBI GI #

6753110

NCBI GeneID

11847

NCBI Accession #

NP_033835.1

UniProt Primary Accession #

O08691

UniProt Related Accession #

O08691

GenBank Nucleotide #

NM_009705.3

NCBI Official Full Name

arginase-2, mitochondrial

NCBI Official Synonym Full Names

arginase type II

NCBI Official Symbol

Arg2

NCBI Official Synonym Symbols

AII; AU022422

UniProt Protein Name

Arginase-2, mitochondrial

UniProt Synonym Protein Names

Kidney-type arginase; Non-hepatic arginase; Type II arginase

Protein Family

Arginase

UniProt Gene Name

Arg2

UniProt Entry Name

ARGI2_MOUSE

NCBI Protein Information

arginase-2, mitochondrial

UniProt Comments for Arg2

ARG2: May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. Belongs to the arginase family.

Protein type: Hydrolase; Mitochondrial; EC 3.5.3.1; Amino Acid Metabolism - arginine and proline

Cellular Component: mitochondrion

Molecular Function: arginase activity; hydrolase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; metal ion binding; nitric-oxide synthase binding

Biological Process: arginine catabolic process to ornithine; arginine metabolic process; negative regulation of nitric-oxide synthase activity; negative regulation of striated muscle contraction; striated muscle contraction; urea cycle

Research Articles on Arg2

1. arginase 2 impairs endothelial autophagy independently of the L-arginine ureahydrolase activity through activation of RPS6KB1 and inhibition of PRKAA, which is implicated in atherogenesis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Arg2 recombinant protein

Reference Product	PubMed Publications
Nos3 recombinant protein	>20 publications with Arg2 and Nos3
Nos2 recombinant protein	>17 publications with Arg2 and Nos2
Nos1 recombinant protein	>10 publications with Arg2 and Nos1
Oat recombinant protein	>6 publications with Arg2 and Oat
Asl recombinant protein	>3 publications with Arg2 and Asl
Otc recombinant protein	>2 publications with Arg2 and Otc

Pathways associated with Arg2 recombinant protein

Products by Pathway	Pathway Diagram
Amino Acid Metabolism Pathway antibodies	Amino Acid Metabolism Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Arginine Biosynthesis Pathway antibodies	Arginine Biosynthesis Pathway Diagram
Arginine Biosynthesis Pathway antibodies	Arginine Biosynthesis Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram

Diseases associated with Arg2 recombinant protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>31 publications with Arg2 and Disease Models, Animal
Cardiovascular Diseases Antibodies	>27 publications with Arg2 and Cardiovascular Diseases
Inflammation Antibodies	>23 publications with Arg2 and Inflammation
Nervous System Diseases Antibodies	>22 publications with Arg2 and Nervous System Diseases
Lung Diseases Antibodies	>19 publications with Arg2 and Lung Diseases
Brain Diseases Antibodies	>17 publications with Arg2 and Brain Diseases
Asthma Antibodies	>12 publications with Arg2 and Asthma
Hypertension Antibodies	>12 publications with Arg2 and Hypertension
Kidney Diseases Antibodies	>10 publications with Arg2 and Kidney Diseases
Heart Diseases Antibodies	>9 publications with Arg2 and Heart Diseases

Organs/Tissues associated with Arg2 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>65 publications with Arg2 and Brain
Intestine Antibodies	>24 publications with Arg2 and Intestine
Thyroid Antibodies	>9 publications with Arg2 and Thyroid
Prostate Antibodies	>6 publications with Arg2 and Prostate
Eye Antibodies	>5 publications with Arg2 and Eye
Thymus Antibodies	>3 publications with Arg2 and Thymus
Embryonic Tissue Antibodies	>2 publications with Arg2 and Embryonic Tissue
Ovary Antibodies	>1 publications with Arg2 and Ovary
Mammary Gland Antibodies	>1 publications with Arg2 and Mammary Gland