Mus Caroli SP100 Recombinant Protein – Cat# MBS1231845

Nuclear Autoantigen Sp-100 (SP100) Mus Caroli Recombinant Protein

Name: SP100 Recombinant Protein; Mus Caroli; MyBioSource
Brand: MyBioSource
SKU: MBS1231845
Price: 1265 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1231845

MBS1231845 is a recombinant protein targeting Sp100. Also known as Recombinant Mus caroli Nuclear autoantigen Sp-100 (Sp100). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1265 / 0.05 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nuclear autoantigen Sp-100 (Sp100), Recombinant Protein

Full Product Name

Recombinant Mus caroli Nuclear autoantigen Sp-100 (Sp100)

Product Gene Name

Sp100 recombinant protein

Product Synonym Names

Nuclear autoantigen Sp-100; Nuclear dot-associated Sp100 protein; Speckled 100 kDa

Sequence

MEDSNASPRM STEHENTEMH PFEYMFKHFK TQKVAISNAI RSTFPFLESL RDREFITGKM YEDLIDSCRS LVPVDKVIYK ALDELEKKFD VTVLWELFNE VNMEKYPDLN PIRRSFECVF PNELSFQGID RGNPNSQLSL EQGPSASYSQ GSLNGSSLDL SSSEGWRSND RRNSNLMQAN QTENHQLAES PGHLDSCELQ VQLNNGDATP ESYSLLPQHE ERAVQLNNEF QINPCFVQLI DVKKENSSFS LAGNQQTRAR TNQNEDSEVI ELSSGDSDDG ENFSEATTTI PSQPAPAYSR TPPTLRTDRR GDTSDTESSI IIRRRKRTGR KKRERLGSYL IRNIKIPMKT SWKTAVLARS ANTSSQRRRK RGPRIPREEN ADFGGAELPA VCGNVQGFLN KEKFKQGIYV RSIRSETGRL FTPMDFEIEG NCEKAKNWRQ TIRCKGWTLR ELIQKGVLQD PPRKKKENPR NPRQMKRQVN AL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

34,543 Da

Sequence Positions

1-482aa; full length protein

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O35893

Species

Mus caroli (Ryukyu mouse) (Ricefield mouse)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Sp100 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Sp100. It may not necessarily be applicable to this product.

NCBI GI #

13878773

NCBI Accession #

O35893.2

UniProt Primary Accession #

O35893

UniProt Secondary Accession #

O35894; O35895; O35896; O35974; Q9QWH0

NCBI Official Full Name

Nuclear autoantigen Sp-100

UniProt Protein Name

Nuclear autoantigen Sp-100

UniProt Synonym Protein Names

Nuclear dot-associated Sp100 protein; Speckled 100 kDa

Protein Family

Nuclear autoantigen

UniProt Gene Name

Sp100

UniProt Entry Name

SP100_MUSCR

UniProt Comments for Sp100

Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regulation of telomeres lengthening. May also regulate TP53-mediated transcription and through CASP8AP2, regulate FAS-mediated apoptosis. May also play a role in infection by viruses through mechanisms that may involve chromatin and/or transcriptional regulation ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Sp100 recombinant protein

Reference Product	PubMed Publications
FLNA recombinant protein	>12 publications with Sp100 and FLNA