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Cystathionine Beta-Synthase (CBS) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1236288

This protein acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor.… More details

$1355 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cystathionine beta-synthase (Cbs), Recombinant Protein
Full Product Name
Recombinant Rat Cystathionine beta-synthase (Cbs)
Product Gene Name
Sequence
PSGTSQCEDG SAGCPQDLEV QPEKGQLEKG ASGDKERVWI SPDTPSRCTW QLGRPMADSP HYHTVPTKSP KILPDILRKI GNTPMVRINR ISKNAGLKCE LLAKCEFFNA GGSVKDRISL RMIEDAERAG TLKPGDTIIE PTSGNTGIGL ALAAAVKGYR CIIVMPEKMS MEKVDVLRAL GAEIVRTPTN ARFDSPESHV GVAWRLKNEI PNSHILDQYR NASNPLAHYD DTAEEILQQC DGKVDMLVAS AGTGGTITGI ARKLKEKCPG CKIIGVDPEG SILAEPEELN QTEQTAYEVE GIGYDFIPTV LDRAVVDRWF KSNDDDSFAF ARMLISQEGL LCGGSSGSAM AVAVKAAQEL KEGQRCVVIL PDSVRNYMSK FLSDKWMLQK GFMKEELSVK RPWWWHLRVQ ELSLSAPLTV LPTVTCEHTI AILREKGFDQ APVVNESGAI LGMVTLGNML SSLLAGKVRP SDEVCKVLYK QFKPIHLTDT LGMLSHILEM DHFALVVHEQ IQSRDQAWSG VVGGPTDRNN GVSSKQLMVF GVVTAIDLLN FVAAREQTRK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
52,513 Da
Sequence Positions
2-561, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P32232
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Cbs recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cbs purchase

MBS1236288 is a recombinant protein targeting Cbs. Also known as Recombinant Rat Cystathionine beta-synthase (Cbs). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for Cbs. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cystathionine beta-synthase
NCBI Official Synonym Full Names
cystathionine beta synthase
NCBI Official Symbol
Cbs
UniProt Protein Name
Cystathionine beta-synthase
UniProt Synonym Protein Names
Beta-thionase; Hemoprotein H-450; Serine sulfhydrase
UniProt Gene Name
Cbs
NCBI Protein Information
cystathionine beta-synthase

NCBI Summary for Cbs

catalyzes condensation of serine and homocyteine to cystathione; involved in transsulfuration pathway; regulated by insulin; alternative splicing produces four mRNA species [RGD, Feb 2006]

UniProt Comments for Cbs

Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (PubMed:20149843, PubMed:8558235).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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