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Exocyst Complex Component 3 (EXOC3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1237760

MBS1237760 is a recombinant protein targeting EXOC3. Also known as Recombinant Human Exocyst complex component 3 (EXOC3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1620 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Exocyst complex component 3 (EXOC3), Recombinant Protein
Full Product Name
Recombinant Human Exocyst complex component 3 (EXOC3)
Product Gene Name
EXOC3 recombinant protein
Sequence
MQCEDSTSFF TMKETDREAV ATAVQRVAGM LQRPDQLDKV EQYRRREARK KASVEARLKA AIQSQLDGVR TGLSQLHNAL NDVKDIQQSL ADVSKDWRQS INTIESLKDV KDAVVQHSQL AAAVENLKNI FSVPEIVRET QDLIEQGALL QAHRKLMDLE CSRDGLMYEQ YRMDSGNTRD MTLIHGYFGS TQGLSDELAK QLWMVLQRSL VTVRRDPTLL VSVVRIIERE EKIDRRILDR KKQTGFVPPG RPKNWKEKMF TILERTVTTR IEGTQADTRE SDKMWLVRHL EIIRKYVLDD LIVAKNLMVQ CFPPHYEIFK NLLNMYHQAL STRMQDLASE DLEANEIVSL LTWVLNTYTS TEMMRNVELA PEVDVGTLEP LLSPHVVSEL LDTYMSTLTS NIIAWLRKAL ETDKKDWVKE TEPEADQDGY YQTTLPAIVF QMFEQNLQVA AQISEDLKTK VLVLCLQQMN SFLSRYKDEA QLYKEEHLRN RQHPHCYVQY MIAIINNCQT FKESIVSLKR KYLKNEVEEG VSPSQPSMDG ILDAIAKEGC SGLLEEVFLD LEQHLNELMT KKWLLGSNAV DIICVTVEDY FNDFAKIKKP YKKRMTAEAH RRVVVEYLRA VMQKRISFRS PEERKEGAEK MVREAEQLRF LFRKLASGFG EDVDGYCDTI VAVAEVIKLT DPSLLYLEVS TLVSKYPDIR DDHIGALLAV RGDASRDMKQ TIMETLEQGP AQASPSYVPL FKDIVVPSLN VAKLLK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
85,567 Da
Sequence Positions
1-756, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
608186
3D Structure
ModBase 3D Structure for O60645
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of EXOC3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EXOC3. It may not necessarily be applicable to this product.

NCBI GI #
31083351
NCBI GeneID
11336
NCBI Accession #
NP_009208.2
UniProt Primary Accession #
O60645
UniProt Secondary Accession #
Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4
UniProt Related Accession #
O60645
GenBank Nucleotide #
NM_007277.4
NCBI Official Full Name
exocyst complex component 3
NCBI Official Synonym Full Names
exocyst complex component 3
NCBI Official Symbol
EXOC3
NCBI Official Synonym Symbols
SEC6; Sec6p; SEC6L1
UniProt Protein Name
Exocyst complex component 3
UniProt Synonym Protein Names
Exocyst complex component Sec6
Protein Family
Exocyst complex component
UniProt Gene Name
EXOC3
UniProt Synonym Gene Names
SEC6; SEC6L1
NCBI Protein Information
exocyst complex component 3

NCBI Summary for EXOC3

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
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UniProt Comments for EXOC3

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

Research Articles on EXOC3

1. Sec6 regulate Bcl-2 and Mcl-1 expressions but not Bcl-xl in malignant peripheral nerve sheath tumor cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EXOC3 recombinant protein

 Reference Product  PubMed Publications
 EXOC4 recombinant protein  >12 publications with EXOC3 and EXOC4
 RALA recombinant protein  >3 publications with EXOC3 and RALA
 EXOC2 recombinant protein  >2 publications with EXOC3 and EXOC2
 RHOQ recombinant protein  >1 publications with EXOC3 and RHOQ
 EXOC1 recombinant protein  >1 publications with EXOC3 and EXOC1
 EXOC6 recombinant protein  >1 publications with EXOC3 and EXOC6
 EXOC7 recombinant protein  >1 publications with EXOC3 and EXOC7

Pathways associated with EXOC3 recombinant protein

 Products by Pathway  Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Cargo Trafficking To The Periciliary Membrane Pathway antibodies  Cargo Trafficking To The Periciliary Membrane Pathway Diagram
 Insulin Pathway antibodies  Insulin Pathway Diagram
 Insulin Processing Pathway antibodies  Insulin Processing Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway antibodies  Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway Diagram

Diseases associated with EXOC3 recombinant protein

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >3 publications with EXOC3 and Inflammation
 Carcinoma, Squamous Cell Antibodies  >1 publications with EXOC3 and Carcinoma, Squamous Cell
 Kidney Diseases Antibodies  >1 publications with EXOC3 and Kidney Diseases
 Atherosclerosis Antibodies  >1 publications with EXOC3 and Atherosclerosis
 Chromosome Aberrations Antibodies  >1 publications with EXOC3 and Chromosome Aberrations
 Lung Neoplasms Antibodies  >1 publications with EXOC3 and Lung Neoplasms

Organs/Tissues associated with EXOC3 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with EXOC3 and Brain
 Nerve Antibodies  >4 publications with EXOC3 and Nerve
 Kidney Antibodies  >4 publications with EXOC3 and Kidney
 Blood Antibodies  >2 publications with EXOC3 and Blood
 Muscle Antibodies  >1 publications with EXOC3 and Muscle
 Embryonic Tissue Antibodies  >1 publications with EXOC3 and Embryonic Tissue
 Spleen Antibodies  >1 publications with EXOC3 and Spleen
 Lung Antibodies  >1 publications with EXOC3 and Lung
 Mouth Antibodies  >1 publications with EXOC3 and Mouth
 Liver Antibodies  >1 publications with EXOC3 and Liver
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