Rat UBIAD1 Recombinant Protein – Cat# MBS1240891

Ubia Prenyltransferase Domain-Containing Protein 1 (UBIAD1) Rat Recombinant Protein

Name: UBIAD1 Recombinant Protein; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS1240891
Price: 2315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1240891

MBS1240891 is a recombinant protein targeting Ubiad1. Also known as Recombinant Rat UbiA prenyltransferase domain-containing protein 1 (Ubiad1), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$2315 / 1 mg (E-Coli) +2 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

UbiA prenyltransferase domain-containing protein 1 (Ubiad1), Recombinant Protein

Full Product Name

Recombinant Rat UbiA prenyltransferase domain-containing protein 1 (Ubiad1), partial

Product Gene Name

Ubiad1 recombinant protein

Sequence

AAVQAPGEKI NIQAGETTQV GDTDQQRNDW PEEDRLPERS WRQKCASYVL ALRPWSFSAS LTPVALGSAL AYRSQGVLDP RLLLGCAVAV LAVHGAGNLV NTYYDFSKGI DHKKSDDRTL VDRILEPQDV VRFGVFLYTL GCVCAAYLYY LSTLKLEHLA LIYFGGLSGS FLYTGGIGFK YVALGDLVIL ITFGPLAVMF AYAVQVGSLA IFPLVYAIPL ALSTEAILHS NNTRDMESDR EAGIVTLAIL IGPTLSYILY NTLLFLPYLI FTILATHCSI SLALPLLTSP MAFSLERQFR SQAFNKLPQR TAKLNLLLGL FYVFGIILAP AGSLPRL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

37,026 Da

Sequence Positions

2-338

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for D3ZG27

Species

Rattus norvegicus (Rat)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ubiad1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ubiad1. It may not necessarily be applicable to this product.

NCBI GI #

157819075

NCBI GeneID

313706

NCBI Accession #

NP_001101463.1

UniProt Primary Accession #

D3ZG27

UniProt Related Accession #

D3ZG27

GenBank Nucleotide #

NM_001107993.1

NCBI Official Full Name

ubiA prenyltransferase domain-containing protein 1

NCBI Official Synonym Full Names

UbiA prenyltransferase domain containing 1

NCBI Official Symbol

Ubiad1

NCBI Official Synonym Symbols

RGD1309588

UniProt Protein Name

UbiA prenyltransferase domain-containing protein 1

Protein Family

UbiA prenyltransferase domain-containing protein

UniProt Gene Name

Ubiad1

NCBI Protein Information

ubiA prenyltransferase domain-containing protein 1

UniProt Comments for Ubiad1

Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzyme: coenzyme Q10, also named ubiquinone, plays an important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress ().

Research Articles on Ubiad1

1. In a rat model of chronic kidney disease, there was a decrease in the thoracic aorta expression of Vkor and Ggcx enzymes, and a decrease in the kidney level of vitamin K1 to MK-4 bioconversion enzyme Ubiad1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with Ubiad1 recombinant protein

Disease Name	Pubmed Publications
Corneal dystrophy crystalline of Schnyder Antibodies	>3 publications with Ubiad1 and Corneal dystrophy crystalline of Schnyder
Nervous System Diseases Antibodies	>1 publications with Ubiad1 and Nervous System Diseases
Eye Abnormalities Antibodies	>1 publications with Ubiad1 and Eye Abnormalities
Gout Antibodies	>1 publications with Ubiad1 and Gout
Movement Disorders Antibodies	>1 publications with Ubiad1 and Movement Disorders
Urinary Bladder Neoplasms Antibodies	>1 publications with Ubiad1 and Urinary Bladder Neoplasms
Inflammation Antibodies	>1 publications with Ubiad1 and Inflammation
Neoplasms Antibodies	>1 publications with Ubiad1 and Neoplasms

Organs/Tissues associated with Ubiad1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Pancreas Antibodies	>1 publications with Ubiad1 and Pancreas
Kidney Antibodies	>1 publications with Ubiad1 and Kidney
Connective Tissue Antibodies	>1 publications with Ubiad1 and Connective Tissue