HLA Class I Histocompatibility Antigen, Alpha Chain E (HLA-E) Human Recombinant Protein

Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules.

Isolation and nucleotide sequence of a cDNA clone encoding a novel HLA class I gene.Mizuno S., Trapani J.A., Koller B.H., Dupont B., Yang S.Y.J. Immunol. 140:4024-4030(1988) Cell surface expression of HLA-E interaction with human beta-2 microglobulin and allelic differences.Ulbrecht M., Courturier A., Martinozzi S., Pla M., Srivastava R., Peterson P.A., Weiss E.H.3.0.CO;2-6>Eur. J. Immunol. 29:537-547(1999) HLA-E, F, and G polymorphism genomic sequence defines new variation spanning the nonclassical class I genes.Ishitani A., Miki A., Williams L.M., Moore Y., Geraghty D.E.Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region.Shiina S., Tamiya G., Oka A., Inoko H. HLA-E. A novel HLA class I gene expressed in resting T lymphocytes.Koller B.H., Geraghty D.E., Shimizu Y., Demars R., Orr H.T.J. Immunol. 141:897-904(1988) Ulbrecht M.A new variant of HLA-E*010303 with three synonymous mutations.He X., Xu L., Liu Y., Zeng Y.Cloning of HLA-E cDNA from activated peripheral leukocytes.He X., Xu L., Liu Y., Zeng Y.Polymorphism in the human class I MHC locus HLA-E in Japanese.Ohya K., Kondo K., Mizuno S.Immunogenetics 32:205-209(1990) Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.Nat. Biotechnol. 27:378-386(2009) Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011) Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.O'Callaghan C.A., Tormo J., Willcox B.E., Braud V.M., Jakobsen B.K., Stuart D.I., McMichael A.J., Bell J.I., Jones E.Y.Mol. Cell 1:531-541(1998) Definitive high resolution typing of HLA-E allelic polymorphisms identifying potential errors in existing allele data.Grimsley C., Kawasaki A., Gassner C., Sageshima N., Nose Y., Hatake K., Geraghty D.E., Ishitani A.Tissue Antigens 60:206-212(2002)

Small volumes of HLA-E recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS1243965 is a recombinant protein targeting HLA-E. Also known as Recombinant Human HLA class I histocompatibility antigen, alpha chain E (HLA-E), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.