Murid Herpesvirus 4 K3 Recombinant Protein – Cat# MBS1244489

E3 Ubiquitin-Protein Ligase MIR1 (K3) Murid Herpesvirus 4 Recombinant Protein

Name: K3 Recombinant Protein; Murid Herpesvirus 4; MyBioSource
Brand: MyBioSource
SKU: MBS1244489
Price: 700 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1244489

MBS1244489 is a recombinant protein targeting K3. Also known as Recombinant Murid herpesvirus 4 E3 ubiquitin-protein ligase MIR1 (K3), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$700 / 0.05 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

E3 ubiquitin-protein ligase MIR1 (K3), Recombinant Protein

Full Product Name

Recombinant Murid herpesvirus 4 E3 ubiquitin-protein ligase MIR1 (K3), partial

Product Gene Name

K3 recombinant protein

Sequence

MDSTGEFCWI CHQPEGPLKR FCGCKGSCAV SHQDCLRGWL ETSRRQTCAL CGTPYSMKWK TKPLREWTWG EEEVLAAMEA C

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

22,214 Da

Sequence Positions

1-81. Partial.

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O41933

Species

Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of K3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for K3. It may not necessarily be applicable to this product.

NCBI GI #

9629601

NCBI GeneID

1497186

NCBI Accession #

NP_044852.1

UniProt Primary Accession #

O41933

UniProt Related Accession #

O41933

GenBank Nucleotide #

NC_001826.2

NCBI Official Full Name

BHV4-IE1 homolog

NCBI Official Symbol

GAMMAHV.K3

UniProt Protein Name

E3 ubiquitin-protein ligase MIR1

UniProt Synonym Protein Names

MK3; Modulator of immune recognition 1 homolog; ORF K3; RING-type E3 ubiquitin transferase MIR1Curated

Protein Family

E3 ubiquitin-protein ligase

UniProt Gene Name

NCBI Protein Information

BHV4-IE1 homolog

UniProt Comments for K3

E3 ubiquitin-protein ligase that mediates ubiquitination of host surface class I (MHC-I) H-2D(b)/H2-D1 and H-2K(b)/H2-K1 molecules before they exit the endoplasmic reticulum, leading to their degradation by the endoplasmic reticulum-associated degradation (ERAD) system, thus blocking the immune detection of virus-infected cells. Mediates ubiquitination of lysine, as well as serine and threonine residues present in the cytoplasmic tail of surface class I molecules. Promotes ubiquitination of hydroxylated serine or threonine residues via ester bonds instead of the classical isopeptide linkage.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.