Human RHBDL1 Recombinant Protein – Cat# MBS1246448

Rhomboid-Related Protein 1 (RHBDL1) Human Recombinant Protein

Name: RHBDL1 Recombinant Protein; Rhomboid-Related Protein 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1246448
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1246448

MBS1246448 is a recombinant protein targeting RHBDL1. Also known as Recombinant Human Rhomboid-related protein 1 (RHBDL1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rhomboid-related protein 1 (RHBDL1), Recombinant Protein

Full Product Name

Recombinant Human Rhomboid-related protein 1 (RHBDL1)

Product Gene Name

RHBDL1 recombinant protein

Product Synonym Gene Name

RHBDL1; RHBDL

Product Synonym Names

Recombinant Rhomboid-related protein 1 (RHBDL1); Rhomboid-related protein 1; RRP EC= 3.4.21.105; Rhomboid-like protein 1

Sequence

MGRVEDGGTT EELEDWDPGT SALPAPGIKQ GPREQTGTGP LSQKCWEPEP DAPSQPGPAL WSRGRARTQA LAGGSSLQQL DPENTGFIGA DTFTGLVHSH ELPLDPAKLD MLVALAQSNE QGQVCYQELV DLISSKRSSS FKRAIANGQR ALPRDGPLDE PGLGVYKRFV RYVAYEILPC EVDRRWYFYR HRSCPPPVFM ASVTLAQIIV FLCYGARLNK WVLQTYHPEY MKSPLVYHPG HRARAWRFLT YMFMHVGLEQ LGFNALLQLM IGVPLEMVHG LLRISLLYLA GVLAGSLTVS ITDMRAPVVG GSGGVYALCS AHLANVVMNW AGMRCPYKLL RMVLALVCMS SEVGRAVWLR FSPPLPASGP QPSFMAHLAG AVVGVSMGLT ILRSYEERLR DQCGWWVVLL AYGTFLLFAV FWNVFAYDLL GAHIPPPP

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

48,314 Da

Sequence Positions

1-438

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

Chromosome Location

Chromosome: 16; NC_000016.9 (726075..728267). Location: 16p13.3

OMIM

603264

3D Structure

ModBase 3D Structure for O75783

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RHBDL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RHBDL1. It may not necessarily be applicable to this product.

NCBI GI #

4506525

NCBI GeneID

9028

NCBI Accession #

NP_003952.1

UniProt Primary Accession #

O75783

UniProt Secondary Accession #

Q0VAX4; Q9NQ85; A2IDC0; A2IDC1

UniProt Related Accession #

O75783

GenBank Nucleotide #

NM_003961.1

NCBI Official Full Name

rhomboid-related protein 1

NCBI Official Synonym Full Names

rhomboid, veinlet-like 1 (Drosophila)

NCBI Official Symbol

RHBDL1

NCBI Official Synonym Symbols

RRP; RHBDL

UniProt Protein Name

Rhomboid-related protein 1

UniProt Synonym Protein Names

Rhomboid-like protein 1

UniProt Gene Name

RHBDL1

UniProt Synonym Gene Names

RHBDL; RRP

UniProt Entry Name

RHBL1_HUMAN

NCBI Protein Information

rhomboid-related protein 1; rhomboid-like protein 1; rhomboid, drosophila, homolog of

NCBI Summary for RHBDL1

This gene encodes a protein similar to Rhomboid in Drosophila which is involved in signalling in the Spitz/epidermal growth factor receptor/mitogen-activated protein kinase pathway. The Rhomboid family of proteins consists of intramembrane serine proteases containing several transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

UniProt Comments for RHBDL1

RHBDL1: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Belongs to the peptidase S54 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Protease; EC 3.4.21.105; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: membrane; integral to plasma membrane

Molecular Function: serine-type endopeptidase activity

Biological Process: signal transduction; proteolysis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.