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Myotubularin-Related Protein 5 (SBF1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1246760

MBS1246760 is a recombinant protein targeting SBF1. Also known as Recombinant Human Myotubularin-related protein 5 (SBF1) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1265 / 0.05 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Myotubularin-related protein 5 (SBF1), Recombinant Protein
Full Product Name
Recombinant Human Myotubularin-related protein 5 (SBF1) , partial
Product Gene Name
Sequence
TMSSLVERAC CRDYQRLGLG TLSSSLSRAK SEPFRISPVN RMYAICRSYP GLLIVPQSVQ DNALQRVSRC YRQNRFPVVC WRSGRSKAVL LRSGGLHGKG VVGLFKAQNA PSPGQSQADS SSLEQEKYLQ AVVSSMPRYA DASGRNTLSG FSSAHMGSHG KWGSVRTSGR SSGLGTDVGS RLAGRDALAP PQANGGPPDP GFLRPQRAAL YILGDKAQLK GVRSDPLQQW ELVPIEVFEA RQVKASFKKL LKACVPGCPA AEPSPASFLR SLEDSEWLIQ IHKLLQVSVL VVELLDSGSS VLVGLEDGWD ITTQVVSLVQ LLSDPFYRTL EGFRLLVEKE WLSFGHRFSH RGAHTLAGQS SGFTPVFLQF LDCVHQVHLQ FPMEFEFSQF YLKFLGYHHV SRRFRTFLLD SDYERIELGL LYEEKGERRG QVPCRSVWEY VDRLSKRTPV FHNYMYAPED AEVLRPYSNV SNLKVWDFYT EET
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
211,048 Da
Sequence Positions
1118-1600. Partial,include Myotubularin phosphatase Doamin
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
603560
3D Structure
ModBase 3D Structure for O95248
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SBF1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SBF1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myotubularin-related protein 5
NCBI Official Synonym Full Names
SET binding factor 1
NCBI Official Symbol
SBF1
NCBI Official Synonym Symbols
MTMR5; CMT4B3; DENND7A
UniProt Protein Name
Myotubularin-related protein 5
UniProt Synonym Protein Names
SET-binding factor 1; Sbf1
UniProt Gene Name
SBF1
UniProt Synonym Gene Names
MTMR5; Sbf1
NCBI Protein Information
myotubularin-related protein 5

NCBI Summary for SBF1

This gene encodes a member of the protein-tyrosine phosphatase family. However, the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket. This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation. Mutations in this gene have been associated with Charcot-Marie-Tooth disease 4B3. Pseudogenes of this gene have been defined on chromosomes 1 and 8. [provided by RefSeq, Dec 2014]
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UniProt Comments for SBF1

Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SBF1 recombinant protein

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