Conus Obscurus ALPHA-A-O4B Recombinant Protein – Cat# MBS1251254

Alpha-Conotoxin OIVB (ALPHA-A-O4B) Conus Obscurus Recombinant Protein

Name: ALPHA-A-O4B Recombinant Protein; Conus Obscurus; MyBioSource
Brand: MyBioSource
SKU: MBS1251254
Price: 615 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1251254

MBS1251254 is a recombinant protein targeting Alpha-A-O4b. Also known as Recombinant Conus obscurus Alpha-conotoxin OIVB. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$615 / 0.05 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Alpha-conotoxin OIVB (Alpha-A-O4b), Recombinant Protein

Full Product Name

Recombinant Conus obscurus Alpha-conotoxin OIVB

Product Gene Name

Alpha-A-O4b recombinant protein

Product Synonym Names

Recombinant Alpha-conotoxin OIVB; Alpha-conotoxin OIVB; Alpha-A-O4b; Alpha-A-OIVB

Sequence

CCGVPNAACP PCVCNKTCG

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

1,840 Da

Sequence Positions

1-19aa; Cytoplasmic domain

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for P0C1W8

Species

Conus obscurus (Obscure cone) (Conus halitropus)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Alpha-A-O4b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Alpha-A-O4b. It may not necessarily be applicable to this product.

NCBI GI #

115311691

NCBI Accession #

P0C1W8.1

UniProt Primary Accession #

P0C1W8

NCBI Official Full Name

Alpha-conotoxin OIVB

UniProt Protein Name

Alpha-conotoxin OIVB

Protein Family

Alpha-conotoxin

UniProt Gene Name

Alpha-A-O4b

UniProt Synonym Gene Names

Alpha-A-O4b

UniProt Entry Name

CA4B_CONOB

UniProt Comments for Alpha-A-O4b

Function: Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks the fetal muscle subtype (alpha-1/beta-1/gamma/delta subunits) (IC50=66 nM) with 1500/2000-fold greater affinity than the adult (alpha-1/beta-1/epsilon/delta) subtype (IC50=96000 nM). It blocks the currents completely and dissociates rapidly from the fetal muscle receptor. Has no inhibitory activity on various neuronal nAChRs. This toxin causes a reversible paralysis upon injection into gold fish. Ref.1 Ref.2

Subcellular location: Secreted.

Tissue specificity: Expressed by the venom duct.

Domain: The cysteine framework is IV (CC-C-C-C-C).

Sequence similarities: Belongs to the conotoxin A superfamily.

Mass spectrometry: Molecular mass is 1866.5 Da from positions 1 - 19. Determined by FAB. Ref.1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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