Rabbit Anti-JUP Polyclonal Antibody – Cat# MBS125248

Western blot analysis of extracts of NCI-H292 cells, using JUP antibody.
Secondary antibody: HRP Goat Anti-Mouse IgG (H+L) (MBS128212) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

Gamma-Catenin (JUP) Antibody – Rabbit Polyclonal

Name: JUP Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS125248
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS125248

Also known as plakoglobin, gamma-catenin is a member of the Armadillo family of signaling molecules, which includes beta-catenin and the Drosophila protein armadillo (1). This family of proteins is involved in Wnt signaling, which is important in embryonic… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

gamma-Catenin (JUP), Polyclonal Antibody

Full Product Name

Rabbit polyclonal to Human g-Catenin

Product Gene Name

anti-JUP antibody

Product Synonym Gene Name

JUP; ARVD12; CTNNG; DP3; DPIII; PDGB; PKGB

Product Synonym Names

y-Catenin; y-Catenin Rabbit pab Antibody; gamma-Catenin Rabbit pab Antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, mouse, rat

Form/Format

Liquid

Purity/Purification

Affinity purified

Concentration

1mg/ml (lot specific)

Preparation and Storage

Upon delivery aliquot and store at -20 degree C or -80 degree C

Molecular Weight

81,745 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (39910859..39942964, complement). Location: 17q21

OMIM

173325

3D Structure

ModBase 3D Structure for P14923

Immunogen

A fusion protein of human g-Catenin

Storage Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-JUP antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-JUP antibody

WB: 1/100-500; IHC: 1/50-100

Product References and Citations for anti-JUP antibody

1. Zhurinsky, J. et al. (2000) J. Cell Sci. 113 (Pt 18), 3127-3139.
2. Wodarz, A. and Nusse, R. (1998) Annu. Rev. Cell Dev. Biol. 14, 59-88.
3. Polakis, P. (1999) Curr. Opin. Genet. Dev. 9, 15-21.
4. Zhurinsky, J. et al. (2000) Mol. Cell Biol. 20, 4238-4252.
5. Charpentier, E. et al. (2000) J. Cell Biol. 149, 503-520.

Other Notes

Small volumes of anti-JUP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JUP purchase

MBS125248 is an antibody targeting JUP. Also known as Rabbit polyclonal to Human g-Catenin. Reactive in Human, mouse, rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for JUP. It may not necessarily be applicable to this product.

NCBI GI #

4504811

NCBI GeneID

3728

NCBI Accession #

NP_002221.1

UniProt Primary Accession #

P14923

UniProt Secondary Accession #

Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9

UniProt Related Accession #

P14923

GenBank Nucleotide #

NM_002230.2

NCBI Official Full Name

junction plakoglobin

NCBI Official Synonym Full Names

junction plakoglobin

NCBI Official Symbol

JUP

NCBI Official Synonym Symbols

DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12

UniProt Protein Name

Junction plakoglobin

UniProt Synonym Protein Names

Catenin gamma; Desmoplakin III; Desmoplakin-3

Protein Family

Junction plakoglobin

UniProt Gene Name

JUP

UniProt Synonym Gene Names

CTNNG; DP3

UniProt Entry Name

PLAK_HUMAN

NCBI Protein Information

junction plakoglobin; catenin gamma; desmoplakin-3; gamma-catenin; desmoplakin III; catenin (cadherin-associated protein), gamma 80kDa; catenin (cadherin-associated protein), gamma (80kD)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-JUP antibody

Reference Product	PubMed Publications
CTNNA1 antibody	>79 publications with JUP and CTNNA1
DSP antibody	>34 publications with JUP and DSP
DSG2 antibody	>21 publications with JUP and DSG2
SRC antibody	>3 publications with JUP and SRC
CDH2 antibody	>3 publications with JUP and CDH2
CDH1 antibody	>3 publications with JUP and CDH1
FYN antibody	>2 publications with JUP and FYN
EGFR antibody	>2 publications with JUP and EGFR

Pathways associated with anti-JUP antibody

Products by Pathway	Pathway Diagram
Acute Myeloid Leukemia Pathway antibodies	Acute Myeloid Leukemia Pathway Diagram
Acute Myeloid Leukemia Pathway antibodies	Acute Myeloid Leukemia Pathway Diagram
Adherens Junctions Interactions Pathway antibodies	Adherens Junctions Interactions Pathway Diagram
Arf6 Trafficking Events Pathway antibodies	Arf6 Trafficking Events Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Cell Junction Organization Pathway antibodies	Cell Junction Organization Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Cell-cell Junction Organization Pathway antibodies	Cell-cell Junction Organization Pathway Diagram

Diseases associated with anti-JUP antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>134 publications with JUP and Neoplasms
Cardiovascular Diseases Antibodies	>36 publications with JUP and Cardiovascular Diseases
Heart Diseases Antibodies	>35 publications with JUP and Heart Diseases
Heart Defects, Congenital Antibodies	>25 publications with JUP and Heart Defects, Congenital
Breast Neoplasms Antibodies	>18 publications with JUP and Breast Neoplasms
Lung Diseases Antibodies	>14 publications with JUP and Lung Diseases
Kidney Diseases Antibodies	>10 publications with JUP and Kidney Diseases
Cell Transformation, Neoplastic Antibodies	>9 publications with JUP and Cell Transformation, Neoplastic
Immune System Diseases Antibodies	>8 publications with JUP and Immune System Diseases
Liver Neoplasms Antibodies	>7 publications with JUP and Liver Neoplasms

Organs/Tissues associated with anti-JUP antibody

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>35 publications with JUP and Heart
Skin Antibodies	>26 publications with JUP and Skin
Lung Antibodies	>23 publications with JUP and Lung
Lymph Antibodies	>18 publications with JUP and Lymph
Muscle Antibodies	>18 publications with JUP and Muscle
Lymph Node Antibodies	>18 publications with JUP and Lymph Node
Blood Antibodies	>16 publications with JUP and Blood
Kidney Antibodies	>12 publications with JUP and Kidney
Mouth Antibodies	>10 publications with JUP and Mouth
Bladder Antibodies	>9 publications with JUP and Bladder