Drosophila Willistoni DwilGK11148 Recombinant Protein – Cat# MBS1255553

Spastin (Spas) (DwilGK11148) Drosophila Willistoni Recombinant Protein

Name: DwilGK11148 Recombinant Protein; Drosophila Willistoni; MyBioSource
Brand: MyBioSource
SKU: MBS1255553
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1255553

MBS1255553 is a recombinant protein targeting DwilGK11148. Also known as Recombinant Drosophila willistoni Spastin (spas). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Spastin (spas) (DwilGK11148), Recombinant Protein

Full Product Name

Recombinant Drosophila willistoni Spastin (spas)

Product Gene Name

DwilGK11148 recombinant protein

Product Synonym Gene Name

spas; GK11148

Product Synonym Names

Recombinant Spastin (spas); Spastin EC= 3.6.4.3

Sequence

MVRTKSSSSS ASSSSQKSPI KSNNGAGGGG SSSSHRQSHR TSIDERKSSS HAHSNNSNVS SSSRRAATAT SGSSSPEGDD DTTTDDLTPT GSSPRSCNGR GHSSVHKQNL YVVSFPIIFL FNVLRSLIYQ LFCIFRYLYG ASTKVLYRPH RRDCNIEIVV QNSKEQQLQL QQHQHNQTLS YSLETGGVSG GSGGEQQVQV QPQRIRALQP LEMATNRPGG GYSPGPGDPL LAKQKHHHRR AFEYISKALK IDEENEGHKE LAIELYRKGI KELEDGIAVD CWNGRGDVWD RAQRLHDKMQ TNLSMARDRL HFLALREEDL QMQRLSLKEK QPAPKQPQRS QTKDPVKQPM LTSLNADPVK MKVRSSGYGP KQNGTSSSRP APSGQTATGA SGRKLTVGTK RPGNLPVTNK SQTLPRNLGS KTTVGAVQRQ PAKTAATPPA VRRQFSSGRN TPPQRSRTPI NNNASSGSGA STPMVSVKGV EQKLVQLILD EIVEGGAKVE WTDIAGQDVA KQALQEMVIL PSVRPELFTG LRAPAKGLLL FGPPGNGKTL LARAVATECS ATFLNISAAS LTSKYVGDGE KLVRALFAVA RHMQPSIIFI DEVDSLLSER SSNEHEASRR LKTEFLVEFD GLPGNPDGDR IVVLAATNRP QELDEAALRR FTKRVYVSLP DEQTRELLLN RLLQKQGSPL DTEALRRLAK ITEGYSGSDL TALAKDAALE PIRELNVEQV KCLDISAMRP ITEKDFHNSL KRIRRSVAPQ SLNSYEKWSQ DYGDITI

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

85,093 Da

Sequence Positions

1-777

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for B4NBP4

Species

Drosophila willistoni (Fruit fly)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DwilGK11148 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DwilGK11148. It may not necessarily be applicable to this product.

NCBI GI #

195445207

NCBI GeneID

6648037

NCBI Accession #

XP_002070222.1

UniProt Primary Accession #

B4NBP4

UniProt Related Accession #

B4NBP4

GenBank Nucleotide #

XM_002070186.1

NCBI Official Full Name

GK11148

NCBI Official Symbol

DwilGK11148

NCBI Official Synonym Symbols

dwil_GLEANR_11385; GK11148

UniProt Protein Name

Spastin

UniProt Gene Name

spas

UniProt Entry Name

SPAST_DROWI

NCBI Protein Information

GK11148 gene product from transcript GK11148-RA; DwilGK11148-PA

UniProt Comments for DwilGK11148

Function: ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse

By similarity. HAMAP-Rule MF_03021

Catalytic activity: ATP + H2O = ADP + phosphate. HAMAP-Rule MF_03021

Subunit structure: Homohexamer. The homohexamer is stabilized by ATP-binding. The homohexamer may adopt a ring conformation through which microtubules pass prior to being severed. Interacts with microtubules

By similarity.

Subcellular location: Membrane; Single-pass membrane protein

Potential. Cytoplasm › cytoskeleton › centrosome

By similarity. Cytoplasm › cytoskeleton

By similarity. Chromosome

By similarity. Note: Colocalizes with cellular microtubule arrays. Localizes to chromosomes from prometaphase/metaphase to anaphase, and this requires microtubules. Localizes to discrete punctate cytoplasmic foci which may correspond to secretory vesicles

By similarity. HAMAP-Rule MF_03021

Sequence similarities: Belongs to the AAA ATPase family. Spastin subfamily.Contains 1 MIT domain.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.