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RUNX1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS125850
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Rabbit polyclonal to Human AML1AML1 (also known as Runx1, CBFA2, and PEBP2alphaB) is a member of the core binding factor (CBF) family of transcription factors (1,2). It is required for normal development of all hematopoietic lineages (3-5). AML1 forms a… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AML1 (RUNX1), Polyclonal Antibody
Full Product Name
AML1 Rabbit pab Antibody
Product Gene Name
Product Synonym Names
RUNX1; AML1 ; AML1 ; RUNX1; AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB ;
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, mouse, rat
Form/Format
Liquid
Purity/Purification
Affinity purification
Preparation and Storage
Upon delivery aliquot and store at -20 degree C or -80 degree C.
Molecular Weight
453
Chromosome Location
Chromosome: 21; NC_000021.8 (36160098..36421595, complement). Location: 21q22.3
OMIM
151385
3D Structure
ModBase 3D Structure for Q01196
Immunogen
A synthetic -peptide of human AML1
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol,
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RUNX1 antibody
Western Blot (WB)
Application Notes for anti-RUNX1 antibody
Western Blot (WB): 1/200-500

Western Blot (WB) of anti-RUNX1 antibody

Western blot analysis of extracts of U-937 cells, using RUNX1 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-RUNX1 Polyclonal Antibody – Cat# MBS125850

Product References and Citations for anti-RUNX1 antibody

1. Wang, S. et al. (1993) Mol Cell Biol 13, 3324-3339. 2. Ogawa, E. et al. (1993) Proc. Natl. Acad. Sci. USA 90, 6859-6863. 3. Okuda, T. et al. (1996) Cell 84, 321-30. 4. Wang, Q. et al. (1996) Proc. Natl. Acad. Sci. USA 93, 3444-3449. 5. North, T.E. et al. (2004) Stem Cells 22, 158-168. 6. Blyth, K. et al. (2005) Nat Rev Cancer 5, 376-387. 7. Tanaka, T. et al. (1996) Mol Cell Biol 16, 3967-79. 8. Zhang, Y. et al. (2004) J Biol Chem 279, 53116-25.

Other Notes

Small volumes of anti-RUNX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RUNX1 purchase

MBS125850 is an antibody targeting RUNX1. Also known as AML1 Rabbit pab Antibody. Reactive in Human, mouse, rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RUNX1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
runt-related transcription factor 1 isoform AML1b
NCBI Official Synonym Full Names
runt-related transcription factor 1
NCBI Official Symbol
RUNX1
NCBI Official Synonym Symbols
AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1
UniProt Protein Name
Runt-related transcription factor 1
UniProt Synonym Protein Names
Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit
UniProt Gene Name
RUNX1
UniProt Synonym Gene Names
AML1; CBFA2; CBF-alpha-2; PEA2-alpha B
UniProt Entry Name
RUNX1_HUMAN
NCBI Protein Information
runt-related transcription factor 1; CBF-alpha-2; PEA2-alpha B; PEBP2-alpha B; oncogene AML-1; AML1-EVI-1 fusion protein; acute myeloid leukemia 1 protein; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit; core-binding factor, runt domain, alpha subunit 2; polyomavirus enhancer-binding protein 2 alpha B subunit

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-RUNX1 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >379 publications with RUNX1 and Bone Marrow
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